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  #1  
Old 04-20-2010
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Smile Which Protein Lost!

A 35-year-old white male presents to his primary care doctor with complaints of headache and malaise. His blood pressure is elevated. He has periorbital and pretibial edema. Urinalysis reveals heavy proteinuria. Which of the following is the most likely principle component of his proteinuria?

A. Albumin
B. Kappa light chains
C. Lambda light chains
D. Tamm-Horsfall protein
E. Transthyretin
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  #2  
Old 04-21-2010
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is it albumin?

heavy proteinuria + peripheral and perorbital edema is a sign on glomerulonephrotic syndrome with high albumin loss in urine causing hypoalbuminemia.
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  #3  
Old 04-21-2010
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i think the ans is A. albumin loss in urine causing massive proteinuria of greater than 3.5g/24hr .
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  #4  
Old 04-21-2010
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i think it is albumin
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  #5  
Old 11-19-2011
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i think it is albumin
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  #6  
Old 11-19-2011
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Default a

i'd go with albumin too
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  #7  
Old 11-19-2011
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I think it is A.

Though all the above mentioned proteins can be excreted in urine, albumin has the maximum contribution towards oncotic pressure in capillaries. And decrease in oncotic pressure results in edema.
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Old 11-19-2011
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I think it is albumin too.
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  #9  
Old 11-20-2011
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Default I think is A

Because albumin controls intravascular pressure. He is also loosing it through the urine... I think.
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