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Old 03-22-2012
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Drug How to memorize the Benzodiazepines

Hey guys, I am getting my ass kicked trying to memorize the different half lives of each benzodiazepine and when to use which one. Anyone have a good mnemonic or tips ? My exam is in 20 days! Any help would be appreciated!
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Old 03-22-2012
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I don't think you should know the specific half lives of each benzo! Just know -

BZ 1 receptor - for SEDATION therefore Sleep disorders = Temazepam & Oxazepam. (Mnemonic I use is "go TO sleep")

BZ 2 receptor - for anxiolysis therefore Anxiety disorders = Lorazepam, Diazepam, Midazolam and Alprazolam.

Out of these benzo's =

Diazepam is the longest acting (24 to 36 hours).
Midazolam is shortest acting (4 hours, therefore its used in pre-op induction anesthesia)

Oxazepam, Temazepam & Lorazepam are metabolized Outside The Liver. (OTL)

Also, they increase the frequency of opening of Cl- channels as compared to Barbiturates which increase the duration.


I think that's about it for Benzodiazepines. lol I don't go into detail about the half lives for EACH one of the benzodiazepines! Not sure if they require you to know that much detail in step 1.
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If U have done uworld ...then thr in one question of benzodiazepines they made a good table of short acting, medium and long acting Bzd's.....its a very good table and just read it......!!!!
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Old 03-22-2012
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Hey guys in my FA i have a note saying alprazolam has thr shortest halflife

But in my kaplan i have it written that midazolam is fastest acting

Which is correct?
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Quote:
Originally Posted by Dr.NickRiviera View Post
Hey guys in my FA i have a note saying alprazolam has thr shortest halflife

But in my kaplan i have it written that midazolam is fastest acting

Which is correct?
Midazolam is the most rapid acting and has the shortest half life (3-6 hours). Alprazolam half life is about 6-12 hours.

Source: http://en.wikipedia.org/wiki/List_of...ent_dose_table
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Old 03-22-2012
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Quote:
Originally Posted by Dr.NickRiviera View Post
Hey guys in my FA i have a note saying alprazolam has thr shortest halflife

But in my kaplan i have it written that midazolam is fastest acting

Which is correct?

according to uworld , short acting bzds r those whose MOA < 10 hrs and long acting > 10hrs.......so both Midazolam and Alprazolam r short acting .....other short acting r Oxazepam and Triazolam .....(remember the pneumonic ATOM )
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Old 08-02-2012
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Alprazolam .5 1 - 2 9 - 20 Bromazepam 3.0 .5 - 4 8 - 30 Chlordiazepoxide 25 1 - 4 24 - 100 Clonazepam .25 1 - 4 19 - 60 Clorazepate 10 variable 1.3 - 120 * (unreliable absorption) Diazepam 5 1 - 2 30 - 200 * Estazolam 1 .5 - .6 8 - 24 Flurazepam 15 .5 - 1 40 - 250 * Halazepam 40 1 - 3 30 - 96 * Ketazolam 7.5 3.2 30 - 200 Lorazepam 1 2 4 8 - 24

It is very important to memorize the different benzodiazepines strengths. This is because they have different doses, and respective uses. Lorazepam side effects are serious, and benzodiazepines are no joke at all.
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Old 04-03-2014
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I've been using Picmonic and they have an awesome picture to help memorize benzodiazepines.

There is a pregnant lady throwing Mercedez Benz-DICE (benzodiazepine) on a craps table. Its hilarious and just by closing my eyes I can easily recall drug mechanism, side effects and indications.
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Old 04-04-2014
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Quote:
Originally Posted by Rahndell View Post
I've been using Picmonic and they have an awesome picture to help memorize benzodiazepines.

There is a pregnant lady throwing Mercedez Benz-DICE (benzodiazepine) on a craps table. Its hilarious and just by closing my eyes I can easily recall drug mechanism, side effects and indications.
Hello, can you elaborate more ?
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Old 04-13-2014
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you can't see it unless you're subscribed but picmonic covers benzodiazepenes with an image/story to remember the details basically
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Old 04-30-2014
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Quote:
Originally Posted by M.Tayeb View Post
Hello, can you elaborate more ?
I attached pictures because its worth showing off. Its against the terms of service to take pictures, and pictures are pretty useless without the interactive webpage, audio/text.
Attached Thumbnails
How to memorize the Benzodiazepines-screen-shot-2014-04-30-3.18.30-pm.png   How to memorize the Benzodiazepines-screen-shot-2014-04-30-3.20.23-pm.png  
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