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Old 04-01-2012
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Pediatrics Mother disease effect on infant?

An infant is born to a woman who has received very little prenatal care. The mother is anxious, complains of heat intolerance and fatigue, and reports that she has not gained much weight despite having an increased appetite. On examination the mom is tachycardic, has a tremor, and has fullness in her neck and in her eyes. The infant is most likely at risk for development of which of the following?


a. Constipation
b. Heart failure
c. Macrocephaly
d. Third-degree heart block
e. Thrombocytosis
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Old 04-03-2012
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macrocephaly....???

please post the answer
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Old 04-03-2012
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macrocephaly
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Old 04-03-2012
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whats the reason?
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Old 04-03-2012
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B .........heart failure
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Old 04-03-2012
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as mother has hyper thyroidism .....low TSH n there fore hogh TRH......TRH can pass placenta n increases fetal TSH n T3 , T4 ......leading to high output heart failure
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Old 04-03-2012
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The answer is b; Heart failure.

The infant is likely at risk for neonatal thyrotoxicosis. Neonatal thyrotoxicosis usually disappears within 2 to 4 months as the concentration of thyroid-stimulating immunoglobulins (7S gamma globulin) diminishes. Unlike TSI, thyroid-stimulating hormone (TSH) does not cross the placenta. All forms of thyrotoxicosis are more common in females, with the exception of neonatal thyrotoxicosis, which has an equal sex distribution. Symptoms include tachycardia and tachypnea, irritability and hyperactivity, low birth weight with microcephaly, severe vomiting and diarrhea, thrombocytopenia, jaundice, hepatosplenomegaly, and heart failure. In severely affected infants, the disease can be fatal if not treated vigorously and promptly. Third-degree heart block is not a feature of this disease, but is sometimes seen in infants born to mothers with systemic lupus erythematosus.
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