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Old 04-10-2012
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Question Lymphedema fluid versus Exudate

whats the difference?
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Old 04-10-2012
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Lymphedema fluid is lymph fluid due to increased capillary pressure in the lymphatic system whereas exudate is a product of inflammation with high LDH, PMN, ...etc
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can you describe the content of lymph edema?
what makes them different from exudate and transudate?
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Old 04-10-2012
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Lymphatic fluid is cell poor, protein poor fluid whereas exudate is cell rich protein rich fluid
transudate has no cells and contains small amount of protein


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Old 04-11-2012
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Quote:
Originally Posted by MedicalExaminer View Post
Lymphatic fluid is cell poor, protein poor fluid whereas exudate is cell rich protein rich fluid
transudate has no cells and contains small amount of protein


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To add to this, exudate is usually as a consequence of increased capillary permeability, a phenomenon mostly seen with inflammation.

Another way to (using lab results) distinguish between transudats and exudates is the lights criteria:

1. Total protein(effusion)/Total protein(serum)>0.5
2. LDH(effusion)/LDH(serum)>0.6
3. LDH(effusion)>2/3 of LDH(serum)

If one of the above is true, it is an exudate.

Hope this helps.
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Old 04-11-2012
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Quote:
Originally Posted by kenlee View Post
can you describe the content of lymph edema?
what makes them different from exudate and transudate?

Protein content:
- Transudate <25 g/L
- Exudate >35 g/dl
- Lymph: intermediate between transudate and exudate in normal conditions, but fluid in lymphedema is classified as exudate. For example, lymphedema of yellow nail syndrome.

Transudate cause pitting edema. Whereas both lymphedema and exudate cause non-pitting edema. Differential cell count of exudate and lymphedema depends upon the condition.

Hope that clears the confusion.
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i jst wanted to know the difference between lymph fluid content compared to exudate.. so in conclusion lymphedema generally has lower protein and nucleated cell than exudate?
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Quote:
Originally Posted by kenlee View Post
i jst wanted to know the difference between lymph fluid content compared to exudate.. so in conclusion lymphedema generally has lower protein and nucleated cell than exudate?
What you can differentiate is normal lymph from exudate, not pathological condition- lymphedema from exudate. Since as I mentioned, often lymphedema is also considered a type of exudate. Composition of both fluids can vary depending upon the condition they are present in.

If I am not yet clear enough, I would be pleased to know why are you interested in differentiating betn the two ?
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Quote:
Originally Posted by slumdog View Post
What you can differentiate is normal lymph from exudate, not pathological condition- lymphedema from exudate. Since as I mentioned, often lymphedema is also considered a type of exudate. Composition of both fluids can vary depending upon the condition they are present in.

If I am not yet clear enough, I would be pleased to know why are you interested in differentiating betn the two ?
golja got me alittle confused but makes sense now, thanks.
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