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Old 04-21-2012
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Drug Antidepressant with few sexual side effects

Which of the following antidepressant has fewer sexual adverse effects?

A) Paroxetine
B) Bupropion
C) Citalopram
D) Amoxapine
E) Doxepine
F) Fluoxetine
G) Fluvoxamine
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Old 04-21-2012
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Old 04-21-2012
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yes it's bupropion for sure, you can also get to it by making exclusion
ALL SSRI and TCA cause sexual dysfunction, well thats if you consider the retrograde ejaculation by SSRI a problem (im sure some man actually like the idea- that goes with saying that some SSRI are used in premature ejaculation treatment).
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Old 04-23-2012
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Quote:
Originally Posted by modesty View Post
yes it's bupropion for sure, you can also get to it by making exclusion
ALL SSRI and TCA cause sexual dysfunction, well thats if you consider the retrograde ejaculation by SSRI a problem (im sure some man actually like the idea- that goes with saying that some SSRI are used in premature ejaculation treatment).
What effect does TCA cause
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Old 04-23-2012
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B. buproprion

used in place of an anti-depressant that causes sexual dysfunction, ie. SSRIs.
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Old 04-23-2012
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Kabutar111 -It causes general dysfunction as it blocks alpha receptors - as the anti hypertensive drugs the alpha blockers who cause sexual dysfunction TCA does so by the same mechanism, if you asked about how will it manifest then i dont know, but probably problems with erection, ejaculation as you are massing with the ANS.
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Old 04-23-2012
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Originally Posted by modesty View Post
Kabutar111 -It causes general dysfunction as it blocks alpha receptors - as the anti hypertensive drugs the alpha blockers who cause sexual dysfunction TCA does so by the same mechanism, if you asked about how will it manifest then i dont know, but probably problems with erection, ejaculation as you are massing with the ANS.
doesn't trazadone do something similar? blocks alpha1 receptors and causes priapism?
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Old 04-23-2012
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Yes trazadone blocks alpha receptors as well, excessive block causes excessive vasodilation leading to prolonged ereaction - priapism. as he also dilates the blood vessels it causes reflex tachycardia - hence his second side effect cardiac arrhythmias. why one causes priapism while the other doesnt, and why alpha blockers like doxazocin dont cause priapism i dont know, but it's probably related to different subtypes of alpha1 receptors and different selectivity of these drugs towards them. Im sure that concept is clear though. :sorry:
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