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#1
04-25-2012
 USMLE Forums Master Steps History: --- Posts: 1,365 Threads: 648 Thanked 585 Times in 354 Posts Reputation: 595

A surgical intern at a major teaching hospital is asked to assist in a study evaluating the risks associated with the development of breast cancer based on population and hospital data. Review of the records of 3000 female patients who underwent breast biopsy for benign breast disease shows that 429 of the women subsequently developed breast cancer. Health department statistics for the county conclude that the lifetime risk for breast cancer in the overall female population is 12.5%. The intern assumes that the hospital biopsy rate accurately reflects the percentage of all patients in the county and nationwide who underwent biopsy for benign breast disease that subsequently developed breast cancer. To calculate the risk for breast cancer attributable to benign breast disease requiring biopsy, what additional information is required?

A. The percentage of all female hospital patients who developed breast cancer
B. The percentage of women in the county who underwent biopsy for benign breast disease
C. The total number of women in the population and the total number of women in the hospital who did not undergo any biopsy and subsequently developed breast cancer
D. The total number of women in the population who have undergone breast biopsy
E. The total number of women who underwent any breast biopsy in the hospital and the total number who subsequently developed breast cancer

#2
04-25-2012
 USMLE Forums Master Steps History: 1+CK+CS Posts: 1,406 Threads: 118 Thanked 642 Times in 407 Posts Reputation: 652

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#3
04-25-2012
 USMLE Forums Master Steps History: 1+CK+CS+3 Posts: 1,684 Threads: 213 Thanked 1,590 Times in 660 Posts Reputation: 1600

I think it would be C as well.

Attributable risk is the Incidence of exposed individuals minus the Incidence in unexposed individuals.

The question is asking for the attributable risk of getting Breast cancer if you have been EXPOSED to a breast disease that required biopsy.

The exposed individuals would be the ones who had a prior breast disease that required biopsy and then developed breast cancer.

The unexposed individuals would be the ones who had no breast disease but still developed breast cancer.

(these types of questions take forever! first reading through such a big question stem and then trying to think about all the options )

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