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Old 05-01-2012
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Question Which of these work on NMDA receptor?

A 43-year-old pregnant woman develops preeclampsia at 32 weeksgestation. Magnesium sulfate, which interacts with NMDA receptors in the central nervous system, is ordered for the prevention of eclamptic seizures until the fetus can be delivered. Which of the following activates the NMDA receptor?

Glycine
Acetylcholine
Substance P
Histamine
Glutamate
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glutamate?

jeee... I love this section of pharma...
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Quote:
Originally Posted by Casandra View Post
glutamate?

jeee... I love this section of pharma...
Which section ?
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Default .

CNS........
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Originally Posted by Casandra View Post
CNS........
When dumped cardio
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Gutamate, excitatory neurotransmitter of the CNS. All the rest doesn't fit
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Glutamate activates NMDA receptors and Ketamine blocks NMDA receptors
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it should be glutamate
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NMDA is a type of glutamate receptor.

Block by Ketamine (for anesthesia) and Felbamate (for epilepsy).
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I'd love to try ketamine
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Glutamate works on NMDA and AMPA receptors on the CNS actually blocking these receptors by felbamate (NMDA) and lamotrigine (AMPA) is used in the treatment of seizures, as we want to decrease the excitation that the glutamate is doing in the CNS and to decrease nerouns discharge.
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the street name for ketamine is kit kat haha

I remembered where i saw a related question with the same answer, it was in UW asking about morphine tolerance:
since glutamate activates NMDA receptors, it increases morphine tolerance
since ketamine blocks NMDA receptors, it decreases morphine tolerance
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Originally Posted by Renaissance View Post
the street name for ketamine is kit kat haha

I remembered where i saw a related question with the same answer, it was in UW asking about morphine tolerance:
since glutamate activates NMDA receptors, it increases morphine tolerance
since ketamine blocks NMDA receptors, it decreases morphine tolerance
how is morphine related to NMDA receptors? doesnt it act on mu opioid receptors?
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Quote:
Originally Posted by Dr.NickRiviera View Post
how is morphine related to NMDA receptors? doesnt it act on mu opioid receptors?
that questions in UW says: it is unknown how exactly ketamine does so
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Old 05-02-2012
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Glutamine is the answer
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