Basal Ganglia Atrophy Diagnosis - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 05-15-2012
alfjof's Avatar
USMLE Forums Veteran
 
Steps History: Step 1 Only
Posts: 251
Threads: 56
Thanked 104 Times in 62 Posts
Reputation: 114
Send a message via Yahoo to alfjof
Neuro Basal Ganglia Atrophy Diagnosis

A 37-year-old male come to your office with dementia, choreiform movements, and tremor that resembles a bird flapping wing. A biopsy of liver shows cirrhosis and increased of AFP. In the slit lamp you observe a rare formation in the eyes(Keyser-Fleischer rings) typical for those patients with this disease. Which of the following is the most likely the diagnosis?

A) Mutation of C2282Y near the MHC locus on chromosome 6
B) activate apoptosis on chromosome 17
C) Mutation in ATP7B code on chromosome 13
D) Gene located on chromosome 4
E) Mutation of AFP gene on chromosome 4p


That one is easy easy please
__________________
Happy to Learn New Concept and Mechanism each Day
Reply With Quote Quick reply to this message



  #2  
Old 05-16-2012
USMLE Forums Addict
 
Steps History: 1+CK+CS
Posts: 194
Threads: 21
Thanked 145 Times in 84 Posts
Reputation: 155
Default

Willson disease is a defect in the transport of copper out of the hepqtocytes which is mediated by ATP7B TRANSPORTER
Reply With Quote Quick reply to this message
  #3  
Old 05-16-2012
K06100's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 730
Threads: 90
Thanked 456 Times in 289 Posts
Reputation: 466
Default C

answer is C........

Mutation in ATP7A gene is menke's disease(kinky hair disease)
__________________
Try Not To Become A Man Of Success But A Man Of Value.
Reply With Quote Quick reply to this message
  #4  
Old 05-16-2012
alfjof's Avatar
USMLE Forums Veteran
 
Steps History: Step 1 Only
Posts: 251
Threads: 56
Thanked 104 Times in 62 Posts
Reputation: 114
Send a message via Yahoo to alfjof
Default

A) Mutation of C2282Y near the MHC locus on chromosome 6: Hemochromatosis
B) activate apoptosis on chromosome 17
C) Mutation in ATP7B code on chromosome 13: Wilson Disease(correct answer)
D) Gene located on chromosome 4: Huntington Disease
E) Mutation of AFP gene on chromosome 4p
__________________
Happy to Learn New Concept and Mechanism each Day
Reply With Quote Quick reply to this message
  #5  
Old 05-16-2012
USMLE Forums Guru
 
Steps History: 1+CK+CS+3
Posts: 457
Threads: 62
Thanked 273 Times in 186 Posts
Reputation: 283
Default

Hey alfjof this one was kinda easier than your earlier questions but i personally love the q's you are putting here, Especially the S3 n S4 sounds one
Quote:
Originally Posted by alfjof View Post
A) Mutation of C2282Y near the MHC locus on chromosome 6: Hemochromatosis
B) activate apoptosis on chromosome 17
C) Mutation in ATP7B code on chromosome 13: Wilson Disease(correct answer)
D) Gene located on chromosome 4: Huntington Disease
E) Mutation of AFP gene on chromosome 4p
Reply With Quote Quick reply to this message
  #6  
Old 05-16-2012
alfjof's Avatar
USMLE Forums Veteran
 
Steps History: Step 1 Only
Posts: 251
Threads: 56
Thanked 104 Times in 62 Posts
Reputation: 114
Send a message via Yahoo to alfjof
Default

Quote:
Originally Posted by kdm0101 View Post
Hey alfjof this one was kinda easier than your earlier questions but i personally love the q's you are putting here, Especially the S3 n S4 sounds one

No problem I will post later
__________________
Happy to Learn New Concept and Mechanism each Day
Reply With Quote Quick reply to this message
  #7  
Old 05-16-2012
DocSikorski's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 1,353
Threads: 94
Thanked 873 Times in 506 Posts
Reputation: 886
Default

Hey thank you for this one!

Btw, what is the difference between Menke and Wilson diseases?
__________________
Ambition is a dream with a V8 engine. EP
Reply With Quote Quick reply to this message
  #8  
Old 05-16-2012
USMLE Forums Guru
 
Steps History: 1+CK+CS+3
Posts: 457
Threads: 62
Thanked 273 Times in 186 Posts
Reputation: 283
Default

i thnk Menke's disease is X-Recessive and the child has stealy hair.Wilson's is A-Recessive
Quote:
Originally Posted by DocSikorski View Post
Hey thank you for this one!

Btw, what is the difference between Menke and Wilson diseases?
Reply With Quote Quick reply to this message



Reply

Tags
Nervous-System-, Pathology-, Step-1-Questions

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
Claudication + Impotance + Leg atrophy mary USMLE Step 2 CK Classic Clues 1 07-09-2016 01:01 PM
Atrophy in conn syndrom kenlee USMLE Step 1 Forum 2 03-23-2012 11:21 PM
Brain biopsy showed a few lacunas in the centrum semiovale, left basal ganglia, and left internal capsule Evergreen USMLE Step 1 Forum 4 11-11-2011 09:35 PM
Basal Ganglia in 13 Pages! Jones_WILLY USMLE Step 1 Forum 4 02-15-2011 08:20 PM
Best treatment for Basal Cell Carcinoma kemoo USMLE Step 1 Forum 3 01-11-2011 11:20 PM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)