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Old 05-26-2012
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Biochemistry G6PD activity; Which Tissue?

A piece of tissue is taken from a biopsy sample and is immediately stained using a fluorescent probe that binds to glucose 6 PO4 dehydrogenase. Examination under a fluorescence microscope shows very poor fluorescence. Which part of the body is this tissue most likely to have been taken from?
1. Caudate lobe of liver
2. Testis
3. Adrenal
4. Adipose tissue
5. Muscle
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Old 05-26-2012
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5. Muscle?
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Old 05-26-2012
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im stuck between adipose and muscle.
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?? Adipose tissue: least metabolically active, therefore least free radical production & least requirement for G6PD activity
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Old 05-26-2012
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Don't adipocytes use NADPH for steroid and fat synthesis.
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Old 05-27-2012
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I think adipose too! What's the answer?
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Old 05-27-2012
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My answer would be muscle......least likely to be involved in anabolism of fats and steroids, hence low G6PD....
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my answer is muscle
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Id say adipose tissue but whr is the question from?
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Old 05-28-2012
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Its muscle. As someone already said, this is where the least amount of NADPH is used.
I made up the question, but the concept was in one of the explanations in uworld.
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Old 05-29-2012
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Quote:
Originally Posted by smanthrav View Post
Its muscle. As someone already said, this is where the least amount of NADPH is used.
I made up the question, but the concept was in one of the explanations in uworld.
Hey, please more interesting similar questions if you can! Thanks!
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