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Old 05-31-2012
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Stats Effect Modification vs Confounding

A new estrogen receptors antagonist is being evaluated for the treatment of post menopausal symptoms. A prospective study shows that in treated woman who smoke, increase the risk of DVT. With RR 1.07 (p<0.01). In treated non-smokers no increase risk of DVT is evident, RR0.96 (p>0.05). The phenomenon described is an example of which of the following?

a) Confounding
b) Selection bias
c) Latent period
d) Effect modification
e) Observe bias

Could some please explain the difference between confounding and effect modification? Thanks!
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Old 05-31-2012
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answer = D...?
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Old 05-31-2012
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Confounding Bias versus Effect Modification!
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Old 05-31-2012
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D.
Effect modification....

Drug here modifies the effect of smocking on DVT...
if its confounding, then Both risk factors work in the same direction..
I.E. here one increases risk and other not, on the other hand, if we talk abt the confounding, both risk factors increases certain disease but its tough to tell which risk factor is strongly associated coz most of the people havè both(Smocking and drinking)...
Î hope dat helped...
Good luck.
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Old 05-31-2012
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Yeah, its D

And thanks rapiddo for the link, but i honestly still don't get it. my brain must be tired!
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Old 05-31-2012
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Quote:
Originally Posted by Pelz View Post
Yeah, its D

And thanks rapiddo for the link, but i honestly still don't get it. my brain must be tired!
yea i dont really get it either lol
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Old 05-31-2012
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lol.

i found this on the step 2 forum

The difference between Effect modification and Confounding bias
more succinct
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