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what is the effect on thrombin time [ time taken for conversion of fibrinogen to fibrin ] in vitamin K deficiency and why ?

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#1 ·
what is the effect on thrombin time [ time taken for conversion of fibrinogen to fibrin ] in vitamin K deficiency and why ?
 
#3 ·
both in dysfibrinogenemias and treatment with heparin.
I just read that much in my UW. With Vit k I think because it agian finally interferes with thrombin formation, i should increase. Correct me if I am wrong.
It's because activated vit K acts as a cofactor
For gamma carboxylation of factor 2 ,7,9,10,
Protein C & S , activated factor 2 in turn is
Needed for conversion of fibrinogen to fibrin
Monomers. Hope that helps.
 
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