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  #1  
Old 06-13-2012
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Immunology A laboratory worker who is "allergic" to fungal spores...

A laboratory worker who is "allergic" to fungal spores is accidentally exposed to a culture of the incriminating fungus on a Friday afternoon. Within 1 hour he develops bouts of sneezing, watery eyes, and nasal discharge. The symptoms seem to subside within a few hours of returning home but reappear the next morning, although the laboratory fungus is no longer present in his home environment. The symptoms persist through the weekend, and on Monday morning, he sees the physician. Which of the following cells is most likely to be seen on microscopic examination of the patient's nasal discharge?

A) Mast cells and neutrophils
B) Lymphocytes and macrophages
C) Neutrophils, eosynophils and CD4+ lymphocytes
D) Neutrophils and CD8+ lymphocytes
E) Mast cells, lymphocytes and macrophages

I would appreciate if you could provide short explanation along with your answer
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Old 06-13-2012
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I would go with E by exclusion.. as its allergic reaction mast cells must be there(remember use of mast cell stabilizers in such cases) and since it's a week already rather than neutrophils lymphocytes n macrophages would fit..

The ans?
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Old 06-13-2012
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i ll go with e and i am guessing
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Old 06-13-2012
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@Rookie and @ricko335 - go fish...
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Old 06-13-2012
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will go with C...
seems the most possible 2 me...
but...no clue what the ans could be...
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Old 06-13-2012
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Samee here!! What's the answer?

Quote:
Originally Posted by one_destiny View Post
will go with C...
seems the most possible 2 me...
but...no clue what the ans could be...
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Old 06-13-2012
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Lol this sounds like a kaplan question...i have no idea
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Old 06-13-2012
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Quote:
Originally Posted by one_destiny View Post
will go with C...
seems the most possible 2 me...
but...no clue what the ans could be...

now we are 3 with the same answer..
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Old 06-13-2012
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Listening

can you reveal the answer sandra?
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answer is (C)
This history is typical of the late-phase reaction in type I hypersensitivity. The initial rapid response is largely
caused by degranulation of mast cells. The late-phase reaction follows without additional exposure to antigen and is
characterized by more intense infiltration by inflammatory cells, such as neutrophils, eosinophils, basophils, monocytes,
and CD4+ lymphocytes. There is more tissue destruction in this late phase



its a robbins and cotran review question... i just copied and pasted, no genuis :P
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Old 06-13-2012
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My answer c...........
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Matched!!!
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i wouldgo with e option,.........tel me wats rite ans.....
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Old 06-13-2012
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Default correct answer :)

Correct answer is C) Neutrophils, eosynophils and CD4+ lymphocytes

This history is typical of the late-phase reaction in type I hypersensitivity. The initial rapid response is largely caused by degranulation of mast cells. The late-phase reaction follows without additional exposure to antigen and is characterized by more intense infiltration by inflammatory cells, such as neutrophils, eosinophils, basophils, monocytes, and CD4+ lymphocytes. There is more tissue destruction in this late phase.

The teaching point of this question was that mast cells are not present in late-phase reaction.
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