Q.How Narcotic overdose results in Neg ionotropy? - USMLE Forums
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Old 09-05-2016
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Default Q.How Narcotic overdose results in Neg ionotropy?

How narcotic overdose results in negative inotropic?Mechanism?
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Old 09-05-2016
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Which class of drugs do u call narcotics?
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Old 09-05-2016
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Narcotics are analgesic drugs that induce sleep ("narcotic" comes from the Greek word "narkos", meaning sleep)and , more specifically refers to opiates such as heroin, morphine and related drugs.

The question is related to FA 2016, P.269.
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Old 09-05-2016
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I realized u were talking about opiates, but i just wanted to make sure.
Well since the only receptor responsible for inotropism in my knowledge was Beta1 in the heart and opiates don't interact with it i googled your question and it seems the Kappa receptor acting opioids may be responsible. It still seems kinda experimental and i'm not sure of how correct this is the only thing i found
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