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Old 06-27-2012
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Default After-radiation tissue damage

The firemen who initially responded to fight the fires from the Chernobyl nuclear reactor accident were exposed to high radiation levels. Some of the men received dosages exceeding 5000cGy. Within hours, many became extremely ill. Damage to which of the following tissues most likely led to this findings?

a) bone marrow
b) cerebellum
c) small intestine
d) heart
e) lungs
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Old 06-27-2012
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c) small intestine
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Old 06-27-2012
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a) bone marrow
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Old 06-27-2012
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Quote:
Originally Posted by Casandra View Post
The firemen who initially responded to fight the fires from the Chernobyl nuclear reactor accident were exposed to high radiation levels. Some of the men received dosages exceeding 5000cGy. Within hours, many became extremely ill. Damage to which of the following tissues most likely led to this findings?

a) bone marrow
b) cerebellum
c) small intestine
d) heart
e) lungs
Well, radiation is toxic to rapidly dividing cells right?
So i'd think C.small intstinal epithelial cells OR A. Bone marrow

Since the effect seems to be actue(hours) I would go with C. SMALL INTESTINE because i dont think bone marrow toxicity would manifest so quickly
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Old 06-28-2012
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Default correct answer

Correct answer is b) cerebellum

The cerebral syndrome occurs within hours in persons exposed to a massive total-body radiation dose. Dosages of 200 to 700 cGy can be fatal, because of injury to radiosensitive marrow and gastrointestinal tract; but death occurs after days to weeks, not hours.

Cardiac and skeletal muscle tissue is relatively radioresistant. Early findings in radiation lung injury include oedema; interstitial fibrosis develops over years in those who survive the injury.
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