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Old 06-28-2012
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Default cause of the following autopsy findings???

A study is conducted to identify causes of neuronal loss in patients 18 to 90 years old who died in the hospital from a natural manner of death and who had autopsies performed. Histologic sections are taken from multiple areas of the brain in each patient. The sections are analyzed for the appearance of red, shrunken neurons, decreased numbers of neurons, or absent neurons. A subset of patients is identified in which the hippocampal pyramidal cells, the cerebellar Purkinje cells, and the superior parasagittal neocortical pyramidal cells are affected. The medical records of these patients are reviewed to determine what risk factors for neuronal loss were present before death. What condition is most likely to be the major cause of neuronal loss in this subset of patients?
(A) Autoimmunity
(B) Chemotherapy
(C) Diabetes mellitus
(D) HIV infection
(E) Global hypoxia
(F) Lead ingestion
(G) Poor nutrition
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Old 06-28-2012
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Quote:
Originally Posted by anomali View Post
A study is conducted to identify causes of neuronal loss in patients 18 to 90 years old who died in the hospital from a natural manner of death and who had autopsies performed. Histologic sections are taken from multiple areas of the brain in each patient. The sections are analyzed for the appearance of red, shrunken neurons, decreased numbers of neurons, or absent neurons. A subset of patients is identified in which the hippocampal pyramidal cells, the cerebellar Purkinje cells, and the superior parasagittal neocortical pyramidal cells are affected. The medical records of these patients are reviewed to determine what risk factors for neuronal loss were present before death. What condition is most likely to be the major cause of neuronal loss in this subset of patients?
(A) Autoimmunity
(B) Chemotherapy
(C) Diabetes mellitus
(D) HIV infection
(E) Global hypoxia
(F) Lead ingestion
(G) Poor nutrition
you listed the watershed zones,therefore is choose option
?Eeeee
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Old 06-28-2012
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Poor nutrition. Alcohol abuse would be the best possible answer for this Q.
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Old 06-29-2012
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Will go with E.
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Old 06-29-2012
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the answer is E......global cerebral hypoperfusion....
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Old 06-29-2012
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Hi, yup E, notice the fact thay the neurons are red, also the ones which are affected purkinje cells and pyramidal cells these cells are most sensitive for ischemia and will be the ones to get affected first, with the hippocampal cells.

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