Enzymes and Alcoholic Hypoglycemia! - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 06-29-2012
USMLE Forums Master
 
Steps History: 1+CK+CS
Posts: 1,039
Threads: 189
Thanked 557 Times in 318 Posts
Reputation: 567
Biochemistry Enzymes and Alcoholic Hypoglycemia!

A 55-year-old alcoholic was brought to the ER by his friends. During their usual nightly gathering at the local bar, he had passed out and they had been unable to revive him. The physician ordered an injection of thiamine followed by overnight parenteral glucose. The next morning the patient was alert and coherent, serum thiamine was normal, and blood glucose was 73mg/dl (4mM). The IV line was removed and he was taken home. At the time of discharge from the hospital, which of the following proteins would have no significant physiologic activity in this patient?

a) Malate dehydrogenase
b) Glukokinase
c) Alpha-ketoglutarate dehydrogenase
d) GLUT 1 transporter
e) Phosphofruktokinase-1

Reply With Quote Quick reply to this message
The above post was thanked by:
bibo (07-02-2012)



  #2  
Old 06-29-2012
USMLE Forums Addict
 
Steps History: 1+CK+CS
Posts: 196
Threads: 9
Thanked 97 Times in 64 Posts
Reputation: 107
Default

B. Glucokinase.
Reply With Quote Quick reply to this message
  #3  
Old 06-29-2012
koolkiller88's Avatar
USMLE Forums Master
 
Steps History: Step 1 Only
Posts: 864
Threads: 62
Thanked 370 Times in 224 Posts
Reputation: 380
Default Glucokinase

Glucokinase keeps glucose inside liver by changing it into glucose 6 phosphate but this person need glucose. So glucose have to come out.
__________________
One day i will infect these microbes and they will search for "Anti-MEbiotic"....
To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.
Reply With Quote Quick reply to this message
  #4  
Old 06-30-2012
USMLE Forums Master
 
Steps History: 1+CK+CS
Posts: 1,039
Threads: 189
Thanked 557 Times in 318 Posts
Reputation: 567
Default correct answer

yup, it's b) glukokinase - the pt is in a 'glucagon world'
Reply With Quote Quick reply to this message
  #5  
Old 07-02-2012
USMLE Forums Scout
 
Steps History: Not yet
Posts: 35
Threads: 1
Thanked 18 Times in 15 Posts
Reputation: 28
Default

another reason y i was thinking glucokinase was that his blood glucose level is 74, at this level glucokinase never works it has a high Km and high Vmax
Reply With Quote Quick reply to this message
The above post was thanked by:
amit chahar (07-02-2012), bibo (07-02-2012)
  #6  
Old 07-02-2012
USMLE Forums Newbie
 
Steps History: Step 1 Only
Posts: 9
Threads: 1
Thanked 0 Times in 0 Posts
Reputation: 10
Default

yup. , glukakinase= high km...
Reply With Quote Quick reply to this message



Reply

Tags
Biochemistry-, Step-1-Questions

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
Cardiac Enzymes Correlation with Infarct Size? bisho USMLE Step 2 CK Forum 0 05-04-2012 11:22 AM
Enzymes using NAD+ Aditya USMLE Step 1 Forum 1 02-27-2010 01:26 PM
Pancreatic Enzymes MLE-Love USMLE Step 2 CK Mnemonics 0 02-25-2010 08:36 PM
RBC Enzymes Question Krishna USMLE Step 1 Forum 5 12-03-2009 05:47 PM
ABC Enzymes in Biochemisty - Mnemonic samirde USMLE Step 1 Mnemonics 0 11-27-2009 03:43 PM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)