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Old 07-07-2012
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Drug Hair growth, Salt retention, Pericardial effusion!

In 55 year-old man with 4 years history of hypertension treating with a specific drug comes to your office this morning, and you observe an abnormal hair growth, pericardial effusion, and salt retention in him. Which of the following would be the mechanism of action of this drug?

A) 5α-reductase inhibitor
B) α1 antagonist inhibitor
C) Direct inhibit Na+ K+ ATP
D) K+ channel opener and relaxes the vascular smooth muscle
D) Indirect inhibition of Na+ Ca2+ exchanger/antiport



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Old 07-07-2012
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Default my answer :)

D) K+ channel opener and relaxes the vascular smooth muscle

It's minoxidil.

The mechanism by which it promotes hair growth is not clear.
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Old 07-07-2012
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D)...No doubt...
Minoxidil...
Excluded all other ones this is the only one which I think s responsible for abnormal hair growth..and thats why we use it sometimes..!!
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