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Old 07-06-2010
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Drug Drug of choice for this?

A 28-year-old female complains to her doctor that she is in danger of losing her job. She states that she is late to work almost everyday because, before she leaves for work, she must check all of the faucets to make sure the water is turned off. She also needs to repeatedly check to make sure that her stove is off. When she is finally ready to leave, she returns from her car several times to ensure that her doors and windows are locked. Which of the following drugs will her physician most likely prescribe?

A. Buspirone
B. Chlorpromazine
C. Clomipramine
D. Imipramine
E. Phenelzine
F. Zolpidem
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Old 07-06-2010
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Unhappy my bad

have to revise CNS.
thx
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Old 07-06-2010
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is it C clomipramine
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Old 07-06-2010
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C. clomipramine for OCD
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Old 07-06-2010
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It's "C" clomipramine. The question points towards "OCD" and the drug of choice of OCD is clomipramine.
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Old 07-07-2010
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yup.u re right guys.The correct answer is C. This patient is suffering from obsessive-compulsive disorder. Clomipramine, a tricyclic antidepressant, and the selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine, are effective in this disorder.
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Old 07-07-2010
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Its a little off topic but ........if we have to chose between SSRIs and Clomipramine. What would be the drug of choice between these two drugs.
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Old 07-07-2010
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Help drug for ocd

in d given option's answer is C.but if selective serotonin reuptake blocker's are given then wouldn't they be a better choice??
and can some one pls explain why clomipramine out of other TCA's???
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Old 07-07-2010
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Post drug for ocd

Clomipramine possesses the highest in vitro affinity for Serotonin transporter than the TCAs, which justifies its use for the treatment of OCD along with the other SSRIs.

But i think if we have to chose b/t clomipramine and SSRIs, SSRIs are a better option owing to less side effects....
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Old 07-07-2010
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Help doc for ocd

Quote:
Originally Posted by doc_study View Post
Clomipramine possesses the highest in vitro affinity for Serotonin transporter than the TCAs, which justifies its use for the treatment of OCD along with the other SSRIs.

But i think if we have to chose b/t clomipramine and SSRIs, SSRIs are a better option owing to less side effects....
i agree..SSRI are much better choice because of not only less s/e also less drug interactions..
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Old 08-17-2010
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Thumbs Up yes........ans would be C only.................

yes, my dear friends ...........Ans is C.CLOMIPRAMINE...........The serotonergic TCA.
The seletive SSRIs such as Fluoxetine,paroxetine,sertraline,citalopram are also effective..................
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