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Old 07-17-2012
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Stats Latent Period and Lead Time Bias!

Hey guys,

is there any clear clue about these two confusing terms,
lead time bias, and latent period bias?

Anyone would help with this, much appreciated.
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Old 07-17-2012
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Lead time bias is the bias that occurs when two tests for a disease are compared, and one test (the new, experimental one) diagnoses the disease earlier, but there is no effect on the outcome of the disease—it may appear that the test prolonged survival, when in fact it only resulted in earlier diagnosis when compared to traditional methods. It is an important factor when evaluating the effectiveness of a specific test

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Old 07-18-2012
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thank you very much, that was a very nice explanation.
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Old 07-18-2012
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What is latent period ?


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Old 07-18-2012
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Quote:
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What is latent period ?


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as far as I know, latent time is the time needed for certain exposure(drug, supplements, radiation, etc.) to exert their effects, and it's not related to comparing two tests for a detection difference.
for example, taking antioxidants would prevent certain kinda tumors, but after for instance 5 years, so studying the effect before that five years period will give different results.
that's my personal understanding.
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Old 07-18-2012
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Quote:
Originally Posted by husseinalaa View Post
as far as I know, latent time is the time needed for certain exposure(drug, supplements, radiation, etc.) to exert their effects, and it's not related to comparing two tests for a detection difference.
for example, taking antioxidants would prevent certain kinda tumors, but after for instance 5 years, so studying the effect before that five years period will give different results.
that's my personal understanding.
you r right. seems everyone is studying the UW explanations ;D
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Quote:
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you r right. seems everyone is studying the UW explanations ;D
what else we got? lol
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Default lead time versus latency period

Quote:
Originally Posted by husseinalaa View Post
Hey guys,

is there any clear clue about these two confusing terms,
lead time bias, and latent period bias?

Anyone would help with this, much appreciated.
Lead Time Bias -- though you are informed ahead of time that a disease outcome will occur, the course of the disease remains unchanged.

Latency Period -- the period of time when no effects are observed because requirements for the effects have not yet been met.
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