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Old 07-22-2012
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Lungs Airway Changes in a Smoker!

A 65-year-old man who smokes one pack of cigarettes a day has dyspnea upon exertion and easy fatigability. The fatigue may be due to the increased amount of work required to breathe. Which of the following is most likely causing this fatigue?

a) Increased airway resistance due to increased dynamic compression of small airways
b) Increased compliance of the chest wall
c) Increased production of pulmonary surfactant
d) Increased vital capacity due to destruction of alveoli
e) Widening of larger airways
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Old 07-22-2012
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A......???
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Matched!!!
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Old 07-22-2012
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A..

Dyspnea predominant-- emphysema.. Trapping of air in alveoli due to collapsed Terminal bronchioles..
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Old 07-22-2012
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A - Increased airway resistance
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What about B?
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Old 07-22-2012
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I go for B... he has emphysema and increase chest wall compliance. Air is trapped due to the emphysema.... I think A would be restrictive pulmonary disease.
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Smoking is disease small airways so probably is A
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Old 07-23-2012
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Default correct answer :)

Correct answer is a) Increased airway resistance due to increased dynamic compression of small airways

Increased airway resistance increases the amount of work required to breathe. This effect is likely to occur due to dynamic compression in chronic obstructive pulmonary disease (e.g., emphysema in smokers). Emphysema results in destruction of elastic tissue that normally exerts traction on the small airways, keeping them open. In the absence of this tissue, the airways decrease their diameter, thus increasing the resistance to airflow and the amount of work necessary to breathe.

Option B (Increased compliance of the chest wall) is incorrect. Increased chest wall compliance has no effect on airway resistance.
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Pathology-, Physiology-, Respiratory-, Step-1-Questions

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