Smoker's Impaired Mucus Clearance; Histology and Anatomy! - USMLE Forums
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  #1  
Old 07-22-2012
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Lungs Smoker's Impaired Mucus Clearance; Histology and Anatomy!

A 60-year-old man, who has smoked two packs of cigarettes a day for 46 years, finds that he must constantly “clear his throat” to eliminate mucus. Which of the following structures in the respiratory tract is most responsible for not being able to eliminate mucus?

a) Alveolar bronchiole
b) Alveolar duct
c) Alveolar sac
d) Alveolus
e) Bronchus
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Old 07-22-2012
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I'd go with E
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Old 07-22-2012
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confused between A and E......
final pick-----A
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Old 07-22-2012
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Quote:
Originally Posted by anomali View Post
confused between A and E......
final pick-----A
but why???

i thought pseudostratified ciliated coulmnar epith. is only till the brochioles.

why not E???
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Old 07-22-2012
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u caught me......alveolar bronchiole means respiratory bronchiole right???
if so then answer would be bronchus, since ciliary epithelium extends up to terminal bronchioles
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Old 07-22-2012
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bronchus it is
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Old 07-22-2012
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why bronchus ?it is lined by pseudostratifed columnar epithe ciliated
i go with alveolar duct
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Old 07-22-2012
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Quote:
Originally Posted by cage92 View Post
why bronchus ?it is lined by pseudostratifed columnar epithe ciliated
The man has BRONCHIECTASIS which has screwed his bronchi.Thats why he is unable to clear the mucus he is producing.
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Old 07-22-2012
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you mean chronic bronchitis
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Old 07-22-2012
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Exactly...my bad
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Old 07-22-2012
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Quote:
Originally Posted by Lara View Post
The man has BRONCHIECTASIS which has screwed his bronchi.Thats why he is unable to clear the mucus he is producing.
yes, its the bronchus thats become bad - bronchiectasis in chronic smoker.
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Old 07-23-2012
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Default correct answer :)

Option E (Bronchus) is correct. The patient has chronic bronchitis, the most common lung abnormality in smokers. Cigarette smoke inhibits the motility of cilia, the small “hairs” located on the respiratory epithelium. The cilia normally function to move mucus up and out of the respiratory system. When cilia do not beat properly, mucus tends to stick where it is produced. The bronchus is lined with a pseudostratified columnar epithelium that is ciliated and has goblet cells. These cells produce mucus, but the cilia are unable to move it along the bronchial surface toward the oral cavity. To compensate, the smoker must constantly “clear his throat” to eliminate the mucus. Some mucus-producing goblet cells are found in the terminal (lobular) bronchioles, but the number found in these bronchioles is smaller than the number found in bronchi.

As for A - Mucus-producing cells are not found in the alveolar (respiratory) bronchiole.
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