BCC vs SCC vs Actinic keratosis - USMLE Forums
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Old 07-22-2012
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Skin BCC vs SCC vs Actinic keratosis

guys can any 1 help explain

how to differentiate between Basal cell carcinoma, squamous cell carcinoma and actinic keratosis?

they very confusing.

I know all the 3 are from excess exposure to sunlight
and actinic keratosis has some HORNS and is precoursor for SCC

Anything other than this??? and thing that you frequently see in the question stem!

thanks
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Old 07-22-2012
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well im not great in differentiating these but ill try to elucidate what i know

BCC....location is imp here...typically they occur in the face region above the line joining nares and helix of the ear( upper face--mostly near the inner canthus of the eye), Having said that, they could occur in any sun-exposed area of the skin
another feature is its histology- groups of basal cells with palisading outer layer,locally invasive but do not metastasize, common called rodent ulcer

SCC----sun exposed area of the skin, keratin pearls on histology is the key feature and the ulcers have heaped up margins, remember the secondary causes here--long standing osteomyelitis ulcer, burns wound.etc

Actinic keratosis
-i have no idea apart from the cutaneous horn on how to identify this one....i just remem one pic from uworld

dont worry...there will be enough clues to spot the diagnosis
just read them again from FA or goljan, google the gross and histo slides of these diseases---i think that would be sufficient....

hope this was helpful....would be happy if any1 can add in more stuff
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