Ankylosing Spondylitis Joint Pathology! - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 07-22-2012
USMLE Forums Master
 
Steps History: 1+CK+CS
Posts: 1,039
Threads: 189
Thanked 561 Times in 319 Posts
Reputation: 571
Bones Ankylosing Spondylitis Joint Pathology!

A 48-year-old man has a 25-year history of lower back pain that began in the sacroiliac joints. He has been taking nonsteroidal anti-inflammatory drugs intermittently. He exhibits no sign of fever. Physical examination shows a stooped posture and tenderness in all the vertebral joints. A high-pitched early diastolic murmur is heard in the second intercostal space on the right. A radiograph of the spine shows forward curvature of the spine with fusion of the lumbar vertebrae. Laboratory test detected the HLA-B27 genotype. The disease process in this patient started in which area?

a) Articular cartilage
b) Ligamentous attachments to bones
c) Soft tissue around joints
d) Subchondral bone around the joints
e) Synovial membrane
Reply With Quote Quick reply to this message
The above post was thanked by:
anomali (07-23-2012)



  #2  
Old 07-22-2012
Rookie's Avatar
USMLE Forums Guru
 
Steps History: 1+CK+CS
Posts: 394
Threads: 40
Thanked 218 Times in 99 Posts
Reputation: 228
Default

Damn such kind of Q do appear!! Wel googled it then realised I forgot


Remember The main symptom of AS is inflammatory spinal pain; with time, some patients develop ankylosis and spinal immobility. The pathology mainly affects the entheses, where ligaments, tendons and capsules are attached to the bone
__________________
The Journey of thousand miles begins with a single step.
Reply With Quote Quick reply to this message
  #3  
Old 07-22-2012
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 791
Threads: 76
Thanked 673 Times in 317 Posts
Reputation: 691
Default

im stuck between A and B...not sure
Reply With Quote Quick reply to this message
 
  #4  
Old 07-22-2012
Guest
 
Steps History: ---
Posts: 197
Threads: 9
Thanked 98 Times in 64 Posts
Reputation: 108
Default

B. Enthesitis
Reply With Quote Quick reply to this message
  #5  
Old 07-22-2012
dr.aaos's Avatar
USMLE Forums Scout
 
Steps History: Not yet
Posts: 10
Threads: 2
Thanked 1 Time in 1 Post
Reputation: 11
Default

I think the answer is B

Ankylosing spondylitis is a form of enthesitis which is inflammation to the site of attachment of tendon/ligmanet to the bone

what about the murmur ? is it due to aortic valve involvement, or aortitis for example ?
Reply With Quote Quick reply to this message
  #6  
Old 07-22-2012
Kabutar111's Avatar
USMLE Forums Guru
 
Steps History: Not yet
Posts: 414
Threads: 30
Thanked 87 Times in 70 Posts
Reputation: 97
Send a message via Skype™ to Kabutar111
Default

read it last week ,didn't paid no attention to this point, will go read again now
__________________
There is no shortcut to SUCCESS ,and there is no excuse for FALIURE - by Kabutar111
To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.
Reply With Quote Quick reply to this message
  #7  
Old 07-27-2012
USMLE Forums Master
 
Steps History: 1+CK+CS
Posts: 1,039
Threads: 189
Thanked 561 Times in 319 Posts
Reputation: 571
Default correct answer :)

The correct answer is b) Ligamentous attachments to bones

The radiograph of the spine showing forward curvature of the spine (kyphosis) with ankylosis (fusion) of the lumbar vertebrae, plus a history of lower lumbar pain beginning in the sacroiliac joints, suggests ankylosing spondylitis. The disease process begins in the ligamentous attachment to bones. This disorder is a part of a related group of disorders called seronegative spondyloarthropathies.
Reply With Quote Quick reply to this message
The above post was thanked by:
anomali (07-28-2012), curiousmind (07-27-2012)



Reply

Tags
Musculoskeletal-, Pathology-, Step-1-Questions

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
How to palpate the hip joint? dr spr USMLE Step 2 CS Forum 5 03-18-2012 09:31 PM
Joint pain & inflammation. ag2011n USMLE Step 2 CK Forum 9 09-24-2011 01:24 AM
Q Joint Pain podebrad USMLE Step 2 CK Forum 1 08-03-2011 01:42 PM
Best Initial Management of Ankylosing Spondylitis docoftheworld USMLE Step 2 CK Forum 9 05-29-2011 10:42 PM
55 yo man with monoarthritis of knee joint tkourkou USMLE Step 2 CK Forum 7 03-15-2011 03:26 PM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)