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Old 07-23-2012
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Pediatrics Fever, encephalitis, chorioretinitis, and hepatosplenomegaly in a newborn!

A newborn infant exhibited fever, encephalitis, chorioretinitis, and hepatosplenomegaly. The attending pediatrician explained to a medical student that these signs resulted from a transplacental infection. She asked the student which one of the following could most likely be eliminated as the transplacental infection responsible for this infantís signs.

a) Cytomegalovirus
b) Herpes simplex virus
c) Human immunodeficiency virus
d) Rubella virus
e) Toxoplasma gondii
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tetrad of C in toxoplasma gondii.....think so
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B....HSV is acquired commonly during delivery
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D)..Rubella..
I think that because its showing none of the classic triad of congenital Rubella syndrome...
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Old 07-23-2012
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Answer is C
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Default B

B- Herpes smplex virus.
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Old 07-23-2012
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Quote:
Originally Posted by Casandra View Post
A newborn infant exhibited fever, encephalitis, chorioretinitis, and hepatosplenomegaly. The attending pediatrician explained to a medical student that these signs resulted from a transplacental infection. She asked the student which one of the following could most likely be eliminated as the transplacental infection responsible for this infantís signs.

a) Cytomegalovirus
b) Herpes simplex virus
c) Human immunodeficiency virus
d) Rubella virus
e) Toxoplasma gondii
it is B...........
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Old 07-28-2012
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Default correct answer :)

The asnwer is c) Human immunodeficiency virus

They specificaly asked 'which one of the following could most likely be eliminated as the transplacental infection responsible for this infantís signs.' - so it was more of a question on what can be a transplacental infection and what can not, rather than fitting in the clinical findings into one of those infections.
The official explanation:

Although human immunodeficiency virus (HIV) infection can be transmitted to offspring by the transplacental route, the usual modes of transmission are during delivery and by ingestion of breast milk. The acute phase of HIV infection has nonspecific symptoms.
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Old 07-28-2012
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Quote:
Originally Posted by Casandra View Post
The asnwer is c) Human immunodeficiency virus

They specificaly asked 'which one of the following could most likely be eliminated as the transplacental infection responsible for this infantís signs.' - so it was more of a question on what can be a transplacental infection and what can not, rather than fitting in the clinical findings into one of those infections.
The official explanation:

Although human immunodeficiency virus (HIV) infection can be transmitted to offspring by the transplacental route, the usual modes of transmission are during delivery and by ingestion of breast milk. The acute phase of HIV infection has nonspecific symptoms.

i agree but HSV is also acquired during delivery right???? its not a typical transplacental infection????
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Quote:
Originally Posted by anomali View Post
i agree but HSV is also acquired during delivery right???? its not a typical transplacental infection????
HSV is both transplacental AND during-delivery acquired.
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