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Old 08-04-2012
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Default Mechanism of action in meningococcal meningitis prophylaxis

In response to an outbreak that involved three cases of serogroup B meningococcal meningitis on the campus of a state university, public health officials were prompted to administer prophylactic pharmacotherapy to all individuals who had been in close contact with the afflicted students. What is the mechanism of action of the most appropriate pharmacotherapeutic agent?

a) Binds to the 50S ribosomal subunit and inhibits peptidyltransferase
b) Inhibition of DNA gyrase and topoisomerase IV
c) Inhibition of folic acid synthesis
d) Inhibition of cell wall synthesis
e) Inhibition of DNA-dependent RNA polymerase
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Old 08-05-2012
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E...drug is rifampicin
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Old 08-06-2012
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Default correct answer

Anomali is right - the answer is e) Inhibition of DNA-dependent RNA polymerase - it's rifampicin.
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