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Old 08-06-2012
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Default Double vision and incoordination - which component destroyed?

A 38-year-old woman complains of excessive fatigue and incoordination and says that she occasionally stumbles and drops things. In response to questioning, she recalls having had an episode of double vision and blurry vision with pain on movement of the eye. The patient most likely has a disease that primarily destroys

a) Astrocytes
b) Ach receptors
c) Striated muscle
d) Gray matter
e) White matter
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Old 08-06-2012
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looks like multiple sclerosis so i would go for E
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Old 08-06-2012
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Default E

Ya i would as go with E
white matter contain mylinated nerve fibers made of oligodendrocytes.
In Multiple sclerosis there are antibodies (IgG) against oligodendrocyes.
Optic nerve is made of oligodendrocytes. Which causing ocular symptoms.
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Old 08-06-2012
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Default correct answer :)

yup, the answer is e) White matter

The patientís clinical findings of incoordination, diplopia, and blurry vision (optic neuritis) are consistent with the diagnosis of multiple sclerosis. This disease is characterized by autoimmune destruction of myelin or oligodendrocytes or both in the central nervous system. Destruction of myelin in the white matter produces depressed areas of demyelination called plaques.
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