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Old 08-15-2012
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Drug Drug to decrease long term mortality in heart failure?

A 65 year old male presents to your office complaining of worsening exertional dyspnea and lower extremity edema. His past medical history is significant for hypertension, and a myocardial infarction 2 years ago. His medication include aspirin and hydrochlorthiazide. addition of one of the following agents is more likely to decrease long term mortality in his patient?

a) furosemide
b) nitrate
c) amiodarone
d) carvedilol
e) milrinone
f) digoxin

pls follow up any suggestive answers with explanations.

Thanks.
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Old 08-15-2012
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I would say D.

This guy is suffering from CHF probably due to his MI 2 years ago. Carvedilol has non-selective beta blocking and alpha-1 blocking properties. It improves systolic function and reverse cardiac remodeling. Anyways, carvedilol and metoprolol are the 2 beta-blockers which is said to improve mortality in patients with CHF.
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Old 08-16-2012
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d) Carvedilol

Studies have shown less mortality with its use
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Cardiovascular-, Pathology-, Pharmacology-

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