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Old 07-26-2010
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Question Oxygen dissociation curve to the left or to the right?

Some one pls tell me why in high altitudes the oxygen dissociation curve shifts towards left.
In high altitudes as Po2 of arterial blood decreases the curve should shift to the right no.....
In biochemistry he is telling the curve shifts towards left....why is it so?

pls explain it guys
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Old 07-26-2010
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Quote:
Originally Posted by devareddy View Post
Some one pls tell me why in high altitudes the oxygen dis curve shifts towards left.in high altitudes as po2 of arterial blood decreases the curve should shift to the right no.....in biochem he is tellin the curve shifts towards left....why is it so?pls xplain it guys
lol.. i noticed that too. he clearly made a mistake. he said left instead of right but when he explained about the PO2 decreasing, he was clearly describing right.

dont worry u are ryte. there will be many more small trivial mistakes that u will notice. the fact that u noticed n did not swallow everything he said is good. u are able to able to tell right from wrong n hence understand the subject!!

carry on with the videos... despite that silly mistake, he is fun to listen to n explains biochem real good.
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Old 07-26-2010
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Thank u for replyin seethal yeah i too felt the same
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Old 07-26-2010
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Arrow He's correct!

It first shifts to the left and then shifts to the right.

Read this
High Altitude Physiology

and read this also
Hemoglobin Dissociation Curve
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Old 07-26-2010
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at high altitude po2 is less so peripheral chemorecepters get activated n pt start hyperventilating....hyperventilation cause co2 washout...so low H+...
with low H+ curve shifts left...
on acclimatization eventually 2,3 BPG is raised so it will shift curve right to its normal position...
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Originally Posted by Sabio View Post
It first shifts to the left and then shifts to the right.

Read this
High Altitude Physiology

and read this also
Hemoglobin Dissociation Curve

hmm... ok.. i read ur links n i understand how it goes to the left first then to the right. but that didnt seem to me how he explained it. he said it like, "so ok, at high altitude it shifts the left. remember that"... it was like he was concluding. and that was misleading i feel. i re-winded 3 times, checked in FA n kaplan physiology before i thought, perhaps he made a mistake.
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Old 07-27-2010
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Originally Posted by Seetal View Post
hmm... ok.. i read ur links n i understand how it goes to the left first then to the right. but that didnt seem to me how he explained it. he said it like, "so ok, at high altitude it shifts the left. remember that"... it was like he was concluding. and that was misleading i feel. i re-winded 3 times, checked in FA n kaplan physiology before i thought, perhaps he made a mistake.
Yeah, I agree with you. He made a mistake.
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