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Old 08-31-2012
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Question Long term complication of splenectomy?

A patient undergoes a splenectomy after an collision. What is the long term complication in this patient?

a) lymphopenia
b) streptococcal infection
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Old 08-31-2012
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Streptoccocal infections ... OPSI is a complication of splenectomy
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Old 08-31-2012
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b) streptococcal infection
actually any infection with an encapsulated bacteria
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Old 08-31-2012
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it's b) streptococcal infections

in splenectomised patients..macrophages are not present to phagocytose encapsulated pathogens....so, pts are vulnerable to infections by encapsulated pathogens like----strep.pneumoniae,hemophilus influenzae,salmonella etc
and also IgM synthesis takes place in spleen..so decrease in complement system too....in splenectomised pts.,platelets and wbc cannot be sequestered so, circulating levels of them increase.....

as for lymphopenia.......seen in splenomegaly/hypersplenism lead to anemia,thrombocytopenia,lymphopenia due to exaggerated sequestration in spleen
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