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  #1  
Old 09-17-2012
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Arrow Belindalimm Daily Questions: Pathology #11

A 28-year-old Caucasian woman with 34 weeks pregnancy is admitted into hospital for C-section delivery. Reviewing of her medical history reveals higher than normal level of blood glucose for the third trimester and she is given glucose-control regimen but still presents a little bit of higher blood glucose level. What is the most likely findings in the neonate right after birth?

A. Hyperglycemia
B. Hyperinsulinemia
C. Hyperlipidemia
D. Normal blood test
E. Hepatomegaly
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  #2  
Old 09-17-2012
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i'll go with B) hyperinsulinemia
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Old 09-17-2012
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B. Hyperinsulemia.

Which will cause hypoglycemia in the baby at the beginning but resolves later on.
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Old 09-17-2012
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Default my answer :)

B. Hyperinsulinemia
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Old 09-17-2012
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Quote:
Originally Posted by belindalimm View Post
A 28-year-old Caucasian woman with 34 weeks pregnancy is admitted into hospital for C-section delivery. Reviewing of her medical history reveals higher than normal level of blood glucose for the third trimester and she is given glucose-control regimen but still presents a little bit of higher blood glucose level. What is the most likely findings in the neonate right after birth?

A. Hyperglycemia
B. Hyperinsulinemia
C. Hyperlipidemia
D. Normal blood test
E. Hepatomegaly
Would go with B
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  #6  
Old 09-17-2012
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Default B

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Would go with B

B is the answer, those babies will be have hypoglicemia!
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Old 09-17-2012
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Hyperinsulinemia


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Old 09-18-2012
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it causes hyperinsulinemia in the child.
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Old 09-18-2012
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Default Yup, the answer is B.

Since the mother's blood glucose is not well-controlled, the remaining high blood glucose will trigger infant's pancreatic beta cell to secrete insulin to counteract the high blood glucose level. When the baby is born, the level of insulin will remain high for a period, which leads to hyperinsulinemia and hypoglycemia in the baby, but the level will return to normal afterwards.
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  #10  
Old 09-26-2012
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Primary hyperinsulinism is a rare but important cause of hypoglycemia in infants and children. It is the most common cause of neonatal hypoglycemia that persists beyond the first few hours of life.

The clinical presentation varies with the age of the child. Early diagnosis and treatment are essential to prevent seizures and neurologic sequelae. Persistent hypoglycemia and inappropriately high concentrations of circulating insulin are diagnostic findings. The concentrations of free fatty acids (FFAs) and ketones (ie, beta-hydroxybutyrate, acetoacetate) are low
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Old 02-23-2013
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Quote:
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Primary hyperinsulinism is a rare but important cause of hypoglycemia in infants and children. It is the most common cause of neonatal hypoglycemia that persists beyond the first few hours of life.

The clinical presentation varies with the age of the child. Early diagnosis and treatment are essential to prevent seizures and neurologic sequelae. Persistent hypoglycemia and inappropriately high concentrations of circulating insulin are diagnostic findings. The concentrations of free fatty acids (FFAs) and ketones (ie, beta-hydroxybutyrate, acetoacetate) are low
why is the concentrations of free fatty acids and ketones low??
plz explain..
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  #12  
Old 02-24-2013
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Default explanation

as insulin is anabolic hormone, so it promotes lipogenesis, and inhibits lipolysis so free fatty acid and ketone bodies( product of lipolysis) are low
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