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  #1  
Old 09-18-2012
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Default Cardiovascular question

A caucasian male is admitted with fever,weight loss and muscle aches.He visited ER several weeks ago for dark stool and malaise.muscle biopsy demonstrates transmural inflammation of arteries with fibrinoid necrosis.some arteries also show fibrous wall thickening.this patients condition is most likely associated with which of the following?

A.Advanse age
B.Smoking
C.Asthma
D.Liver disease
E.Adverse drug reaction
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  #2  
Old 09-18-2012
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Originally Posted by blade View Post
A caucasian male is admitted with fever,weight loss and muscle aches.He visited ER several weeks ago for dark stool and malaise.muscle biopsy demonstrates transmural inflammation of arteries with fibrinoid necrosis.some arteries also show fibrous wall thickening.this patients condition is most likely associated with which of the following?

A.Advanse age
B.Smoking
C.Asthma
D.Liver disease
E.Adverse drug reaction


Im thinking- Polyarteritis Nodosoa, with Hepatitis B?

Last edited by DrSK; 09-18-2012 at 09:54 PM.
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Old 09-18-2012
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Default my answer :)

D.Liver disease - polyarteritis nodosa
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Old 09-19-2012
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Cool I will go with D

Classic polyarteritis nodosa (PAN or c-PAN) is a systemic vasculitis characterized by necrotizing inflammatory lesions that affect medium-sized and small muscular arteries, preferentially at vessel bifurcations, resulting in microaneurysm formation, aneurysmal rupture with hemorrhage, thrombosis, and, consequently, organ ischemia or infarction.
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Old 09-19-2012
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Default D is correct :)

Transmura inflammation of the arterial wall with fibrinoid necrosis is characteristic of Polyarteritis Nodosa(PAN)
In this disease,there is segmental,transmural,necrotising inflammation of medium to small sized arteries.
PAN is associated with hepatitis B infection(option D)
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Old 09-19-2012
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Quote:
Originally Posted by blade View Post
Transmura inflammation of the arterial wall with fibrinoid necrosis is characteristic of Polyarteritis Nodosa(PAN)
In this disease,there is segmental,transmural,necrotising inflammation of medium to small sized arteries.
PAN is associated with hepatitis B infection(option D)
awesome guys
I think I DONT KNOW ANYTHING
KEEP POSTING,LET ME THINK MORE:sorry:
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Old 09-19-2012
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Quote:
Originally Posted by blade View Post
A caucasian male is admitted with fever,weight loss and muscle aches.He visited ER several weeks ago for dark stool and malaise.muscle biopsy demonstrates transmural inflammation of arteries with fibrinoid necrosis.some arteries also show fibrous wall thickening.this patients condition is most likely associated with which of the following?

A.Advanse age
B.Smoking
C.Asthma
D.Liver disease
E.Adverse drug reaction
Liver disease- seems polyarthritis nodusa to me
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