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Old 09-19-2012
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Default covalent binding of antibody to receptor

binding between IgE and mast cell is not covalent
What does it mean?
thanks
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Old 09-19-2012
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I agree IgE

Quote:
Originally Posted by sepideh View Post
binding between IgE and mast cell is not covalent
What does it mean?
thanks


I hope this gelp!
IgE - Epsilon heavy chains
"The heavy and light chains and the two heavy chains are held together by inter-chain disulfide bonds and by non-covalent interactions ....... http://pathmicro.med.sc.edu/mayer/IgStruct2000.htm
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Old 09-19-2012
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Default IgE crosslinking

i dont think any bond was formed.its simply crosslinking of IgE by antigens that trigers mast cell activation alongside other mast cell activation factors. but if any bond atall should exist which i dont know,i think it should be a weak hydrogen bond?
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