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  #1  
Old 09-20-2012
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Default Micro Qs

A JAPANESE 4-year-old child living in a slum is bitten by a rat while sleeping. Two days later, the child develops a rash characterized by discrete erythematous 1-4 mm macules on the extremities and face, most obvious on the --->palms and soles<---. Which of the following organisms is the most likely cause of this child's disease?

A. Borrelia burgdorferi
B. Pseudomonas mallei
C. Pseudomonas pseudomallei
D. Spirillium minus
E. Streptobacillus moniliformis


Last edited by Fuser00; 09-20-2012 at 09:02 AM. Reason: A particular clue
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  #2  
Old 09-20-2012
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Will go with E!
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Old 09-20-2012
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Quote:
Originally Posted by dockhi View Post
Will go with E!
why not other alternatives?
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  #4  
Old 09-20-2012
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may be D) spirillum.....but it's kinda rare

so streptobacillus moniliformis would be the right choice

Last edited by venky2600; 09-20-2012 at 09:07 AM.
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Old 09-20-2012
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Quote:
Originally Posted by Fuser00 View Post
why not other alternatives?
Oh, just guessing here. Can't be Borrelia, it clearly mentiones the rat?
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Old 09-20-2012
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Quote:
Originally Posted by Fuser00 View Post
A JAPANESE 4-year-old child living in a slum is bitten by a rat while sleeping. Two days later, the child develops a rash characterized by discrete erythematous 1-4 mm macules on the extremities and face, most obvious on the --->palms and soles<---. Which of the following organisms is the most likely cause of this child's disease?

A. Borrelia burgdorferi
B. Pseudomonas mallei
C. Pseudomonas pseudomallei
D. Spirillium minus
E. Streptobacillus moniliformis

Haha I would really appreciate if u use some familiar names next time. ;-)
Just a random guess D. Spirillium minus


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  #7  
Old 09-20-2012
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Please post answer with explanation Fuser!
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  #8  
Old 09-20-2012
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Default The correct answer is E

The child has "rat-bite fever." This occurs in two forms with somewhat similar clinical manifestations. The form this child has is the Haverhill fever form, caused by Streptobacillus moniliformis and characterized by a short (often 1-3 days) incubation period. The Haverhill form is more common in the United States than the Sodoku form, which is caused by Spirillium minus, has a 1-4 week incubation period, and is most prevalent in Japan. One of the problems with diagnosing these diseases is that the victims are usually young children, and the bite site may be inapparent by the time the disease becomes severe enough for the child to be taken to a doctor.

Borrelia burgdorferi (choice A) causes Lyme disease, which is characterized by an expanding erythematous rash, arthralgias, and eventual nervous system involvement.

Pseudomonas mallei (choice B) causes glanders, which generally affects horses or humans in close contact with equines.

Pseudomonas pseudomallei (choice C) causes melioidosis, a rare pulmonary disease found mostly in Southeast Asia.

Spirillium minus (choice D) causes the "Sodoku form" of rat-bite fever

I added the clue -- JAPANESE-- for not discard at all letter D, but the most important fact is in relation of the INCUBATION PERIOD
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The above post was thanked by:
dockhi (09-21-2012), koolkiller88 (09-20-2012), step1success (09-20-2012)



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