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  #1  
Old 10-02-2012
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Drug Drug Induced Hyperplastic Gingiva

A patient comes to your office and tells you about her her mouth problems, you examine her and find a hyperplastic gingiva. She tells you that this started after you put her on a drug.

Which drugs can cause her symptom?

a) Minoxidil
b) Nifedipine
c) Finasteride
d) Hydralazine
e) Phenytoin
f) Procainamide
g) Isoniazide
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Old 10-02-2012
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Default my answer :)

2 answers are correct:

b) Nifedipine

and

e) Phenytoin
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Quote:
Originally Posted by Casandra View Post
2 answers are correct:

b) Nifedipine

and

e) Phenytoin
it's just a type of question -> either you know the answer or you don't. I haven't found Nifedipine and gingiva hyperplasia in FA but in KLN, therefore I put it here.
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Default EE

E...phenytoin
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Quote:
Originally Posted by Curacao View Post
it's just a type of question -> either you know the answer or you don't. I haven't found Nifedipine and gingiva hyperplasia in FA but in KLN, therefore I put it here.
it's not a matter of knowing or not, both drugs I mentioned produce gingival hyperplasia. Grab any pamphlet of any "-dypine" or phenytoin and you'll see.
I don't know what FA says. In KLN they specifically say that those both drugs are responsible for this type of side effect.
where is this question from? maybe you should contact the author and tell them to correct it?
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Dihydropiridines and Phenytoin Produce Gingival Hyperlasia as side effect.
Also Cyclosporine is known to cause the same side effect. note that risk for viridans endocarditis and septicemia increases in these patients.

for more info:
http://emedicine.medscape.com/article/1076264-overview
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Quote:
Originally Posted by Casandra View Post
it's not a matter of knowing or not, both drugs I mentioned produce gingival hyperplasia. Grab any pamphlet of any "-dypine" or phenytoin and you'll see.
I don't know what FA says. In KLN they specifically say that those both drugs are responsible for this type of side effect.
where is this question from? maybe you should contact the author and tell them to correct it?
Sorry, maybe you got me wrong. I made it up myself by listening to the videos. I just wanted to mention that I couldn't find these side effects in FA.

With knowing the answer or not I meant: one just has to learn certain side effects and memorize them, some are easy such as reflex tachykardia with b-blockers and make sense but some are just strange. Or can you tell me why there's Hypertrichiosis with the use of topical Minoxidil...

I hope I made it clear what I meant.

Last edited by Curacao; 10-02-2012 at 08:30 AM.
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Quote:
Originally Posted by Curacao View Post
Sorry, maybe you got me wrong. I made it up myself by listening to the videos. I just wanted to mention that I couldn't find these side effects in FA.

With knowing the answer or not I meant: one hast just to learn certain side effects and memorize them, some are easy such as reflex tachykardia with b-blockers.

I hope I made it clear what I meant.
ya, some of them are easy and understandable, some of them or not. but believe me that the more you practice medicine and the more pts you see, those side effects will not be so unfamiliar. but I'm sure you already know that yourself
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yup nifidipine and phenytoin.

Another interesting drug side effect is Livedo reticularis. Any idea which drug causes this side effect?
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Quote:
Originally Posted by drZoe View Post
yup nifidipine and phenytoin.

Another interesting drug side effect is Livedo reticularis. Any idea which drug causes this side effect?
amiodarone
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Quote:
Originally Posted by drZoe View Post
yup nifidipine and phenytoin.

Another interesting drug side effect is Livedo reticularis. Any idea which drug causes this side effect?

amantadine
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Quote:
Originally Posted by drZoe View Post
yup nifidipine and phenytoin.

Another interesting drug side effect is Livedo reticularis. Any idea which drug causes this side effect?
Amantadine.........from Dr Raymond
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Quote:
Originally Posted by Casandra View Post
amantadine
Yes yes i typed amiodarone instead of amantadine
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Quote:
Originally Posted by blade View Post
Amantadine.........from Dr Raymond

my favourite quote:

"The only snow there is in Miami is cocaine..."
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Idea! Drugs causing gingival hyperplasia

(Wikipedia)


Gingival enlargement may also be associated with the administration of three different classes of drugs, all producing a similar response:
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Correcto! Its amantadine!

Hmm here is another one...Which drug causes oligospermia?
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Quote:
Originally Posted by drZoe View Post
Correcto! Its amantadine!

Hmm here is another one...Which drug causes oligospermia?
it's important---sulpha drugs(sulphasalazine)...

here is another one-----which anticancer drug causes cancer??
(i asked it already earlier...but it's kinda important to remember..)
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Quote:
Originally Posted by venky2600 View Post
it's important---sulpha drugs(sulphasalazine)...

here is another one-----which anticancer drug causes cancer??
(i asked it already earlier...but it's kinda important to remember..)
Yup you are right.

Answer> cyclophosphamide>transitional cell Ca of bladder.
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Correct Answer

Quote:
Originally Posted by drZoe View Post
Yup you are right.

Answer> cyclophosphamide>transitional cell Ca of bladder.
ya and also remmeber procarbazine which cause leukemia(leukemogenic)
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