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  #1  
Old 10-03-2012
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Question Rheumatoid arthritis and high creatinine level

A 74-year-old man comes to the physician for a follow-up examination. He has a 3-month history of severe pain and swelling of metacarpophalangeal joints, wrists, elbows, and knees. Previous treatment with aspirin,methotrexate, and naproxen has not relieved his symptoms. He has one kidney. Physical examination shows no other abnormalities. His serum rheumatoid factor is increased, and serum creatinine concentration is 3.8 mg/dL. Which of the following is the most appropriate pharmacotherapy?
(A) Acetaminophen
(B) Colchicine
(C) Etanercept
(D) Gold salts
(E) Indomethacin
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  #2  
Old 10-03-2012
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colchicine..??
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  #3  
Old 10-03-2012
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B. Colchicine????????????
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Old 10-03-2012
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i think its etanercept
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Old 10-03-2012
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Default Cc?

why not Etanecept guys?
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Old 10-03-2012
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Quote:
Originally Posted by blade View Post
why not Etanecept guys?
i'm thinking..she also presents with gout symptoms too due to prior medications
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  #7  
Old 10-03-2012
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Quote:
Originally Posted by venky2600 View Post
i'm thinking..she also presents with gout symptoms too due to prior medications
but colchicine is contraindicated in elderly coupled with his high Rheumatoid factor
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Old 10-03-2012
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Quote:
Originally Posted by blade View Post
but colchicine is contraindicated in elderly coupled with his high Rheumatoid factor
may be ur right and i'm not sure with my answer too....jus my opinion ,thought of giving immunosuppresant with such renal clearance may not be right choice...
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  #9  
Old 10-03-2012
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Originally Posted by venky2600 View Post
may be ur right and i'm not sure with my answer too....jus my opinion ,thought of giving immunosuppresant with such renal clearance may not be right choice...
lol...i await his answer.i always feel there is a catch in every question posted here.i may be totally offtrack
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Old 10-03-2012
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The answer is c)
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Default my asnwer C

Is there any treatment -protocol wich suggest the use of colchicine in RA????
my asnwe is Etanercept... use it for severe cases of RA
Gold salts are nephrotoxic
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  #12  
Old 10-04-2012
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I agree the answer !

C... eternecept!

(even colchicine cannot be used in renal failure.. it gets excreted via the kidneys ..)
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  #13  
Old 10-05-2012
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Thanks. where did you get the question from?
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