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Old 10-05-2012
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Drug Ciprofloxacin Mechanism of Action

Which of the following drugs has MOA similar to CIPROFLOXACIN?
a) CYTARABINE
B) ETOPOSIDE
C) BUSULFan
d) cisplatin
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Old 10-05-2012
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B)etoposide
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Step 1 - 244 [✔] Step 2 CK - 246 [✔] Step 2 CS [✔] Step 3 - 228 [✔] Match [EMORY SOM] YOG: 2013, 4 Months of USCE University Hospital
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Old 10-05-2012
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B! Ciprofloxacin (Fluoroquinlone) will block DNA topoisomerase II in prokaryotes. Etoposide and Teniposide will block DNA Topoisomerase II in the neoplastic eukaryotic cells.
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Old 10-05-2012
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agree with dockhi explanation----b)etoposide
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ans has already been explained by dochi....
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Quote:
Originally Posted by rupesh View Post
ans has already been explained by dochi....
sorry its dockhi
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Old 10-05-2012
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b) etoposide.

Another interesting relation to topoisomerase I is....which auto antibody is formed against it causing a famous autoimmune disease?
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Quote:
Originally Posted by drZoe View Post
b) etoposide.

Another interesting relation to topoisomerase I is....which auto antibody is formed against it causing a famous autoimmune disease?
it's systemic sclerosis----anti scl-70/anti-topoisomerase
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