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Old 10-09-2012
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Help Rheumatoid Arthritis Anti-CCP Antibody

What is anti CCP antibody?
There is an increase in this in RA?
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As I remember reading somewhere
It is Anti C Citrulline peptide antibody.
Yes it is positive in RA but not that sensitive.
Still I don't have much information about it.


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anti-citrullinated cyclic peptide antibody-------yes, positive in rheumatoid arthritis---
i knew only that it is sensitive than RF but not specific either to confirm it.
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Quote:
Originally Posted by preeti617 View Post
What is anti CCP antibody?There is an increase in this in RA ?
Anti-CCP antibodies are potentially important surrogate markers for diagnosis( positive in 80-90%) and prognosis in rheumatoid arthritis (RA), because they:

are as sensitive as, and more specific than, IgM rheumatoid factors (RF) in early and fully established disease( RF positive in Hep C and other chronic infection)

may predict the eventual development into RA when found in undifferentiated arthritis
are a marker of erosive disease in RA
may be detected in healthy individuals years before onset of clinical RA
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Old 01-21-2013
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Post Re: Rheumatoid Arthritis Anti-CCP Antibody

Quote:
Originally Posted by preeti617 View Post
What is anti CCP antibody?
There is an increase in this in RA?
CCP antibody--Anti-citrullinated protein antibodies or anti-cyclic citrullinated. It is more found in rheumatoid arthritis patients.
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