Tryptase: is the most abundant secretory granule (derived serine proteinase) contained in mast cells. Normal serum levels < 1 ng/ml, the level would be elevated in anaphylactic reactions.
Correct answer is C) Tryptase. Anaphylaxis results from widespread mast cell degranulation and resultant histamine release. Tryptase is also released by mast cell degranulation and since it is an enzyme that is relatively specific to mast cells it is often used as a marker of mast cell activation.
This is a question from UWorld and I thought I'd share it with you, since it's a tricky one (at least from my point of view).
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