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  #1  
Old 10-14-2012
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Thyroid Hyper/hypothyroidism

Pathoma video says hypo & hyperthyroidism causes oligomenorrhea. I thought hyperthyroidism causes oligomenorrhea & hyothyroidism causes menorrhagia. Firstaid doesn't say anything.please clear my confusion.I have my exam soon Thanks.
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Old 10-15-2012
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Default hypo/hyperthyroidism

Both hypo & hyperthyroidism can cause any menstrual abnormality but most common menstrual abnormality in hyperthyroidism is oligomenorrhea/amenorrhea while that in hypothyroidism is menorrhagia (*opposite relation). Hope this clears your doubt.
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Old 10-15-2012
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Ya. Hypo causes oligomenorrhoea and hyper causes menorrhagia. Also note that hypo cause diastolic and hyper causes systolic HTN
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Old 10-15-2012
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Default hypo/hyperthyroidism

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Originally Posted by Janakpriya View Post
Ya. Hypo causes oligomenorrhoea and hyper causes menorrhagia. Also note that hypo cause diastolic and hyper causes systolic HTN
I dont agree with the menstrual abnormalities mentioned by you. According to Harrison 18 ed (pg 2920 & pg 2923) "Women frequently experience oligomenorrhea or amenorrhea (in hyperthyroidism)".

Regarding HTN you are spot on.
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Old 10-15-2012
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Idea!

man this topic is crap and still no specific answer how thyroid disease in hyper or hypo form affect the menstrual cycle, u can't just specify one for each still under research that's why u will see every book is going on his own.
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Old 10-15-2012
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this post might be helpful......

i think hyperthyroidism causes oligomenorrhea
and hypothyroidism causes oligo/menorrhagia according to severity

http://www.women-health-info.com/295...menorrhea.html
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Old 10-12-2013
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Embarrassed mechanism?

Im not sure if this is the exact mechanism- but this is how it was explained to me :

In hypOthyroidism-- you have decreased t3 and decreased t4. This causes TRH to be INCREASED ( trh from hypothalmus)--> We know that TRH stimulates PROLACTIN and hyperprolactinemia cuases decreased LH/FSH --> amenorrhea .**

HypERthyroidism can also cause amenorrhea. The mechanism behind this involves SHBG regulation ( produced in liver). So, hyperthyroidism leads to Increased production of SHBG-- this leads to decreased amount of free estrogen --> decreased chances that you will have an LH peak and therefore AMENORRHEA.


**My confusion now lies in the fact that MTB 2 pg 112 says " hypothryoidism is characterized by almost all bodily processes being slowed down except menstural flow which is INCREASED".

I hope my mechanism hasnt confused anyone. If this is incorrect, please let me know and ill take it down .. dont want to confuse others.
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Old 12-22-2015
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Quote:
Originally Posted by pkul85 View Post
Im not sure if this is the exact mechanism- but this is how it was explained to me :

In hypOthyroidism-- you have decreased t3 and decreased t4. This causes TRH to be INCREASED ( trh from hypothalmus)--> We know that TRH stimulates PROLACTIN and hyperprolactinemia cuases decreased LH/FSH --> amenorrhea .**

HypERthyroidism can also cause amenorrhea. The mechanism behind this involves SHBG regulation ( produced in liver). So, hyperthyroidism leads to Increased production of SHBG-- this leads to decreased amount of free estrogen --> decreased chances that you will have an LH peak and therefore AMENORRHEA.


**My confusion now lies in the fact that MTB 2 pg 112 says " hypothryoidism is characterized by almost all bodily processes being slowed down except menstural flow which is INCREASED".

I hope my mechanism hasnt confused anyone. If this is incorrect, please let me know and ill take it down .. dont want to confuse others.
hmmmm, is it right that prolactin inhibit secretion of FSH and LH?
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Old 12-22-2015
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Yea. Prolactin inhibits GnRH which results in decreased FSH and LH. Its given in first aid. There's a whole page on it
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Old 12-22-2015
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Originally Posted by datson View Post
Yea. Prolactin inhibits GnRH which results in decreased FSH and LH. Its given in first aid. There's a whole page on it
Ohhhh, I see, thanks for your answer
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Old 12-22-2015
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Why in thyroid storm hypotension occur, while in thyrotoxicosis hypertension occur ?
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