Drug effects on Transplanted Heart! - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 10-14-2012
MedicalExaminer's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 824
Threads: 66
Thanked 463 Times in 298 Posts
Reputation: 473
Heart Drug effects on Transplanted Heart!

A 45y/o man recently has been the recipient of heart transplant. Which of the following drug is least likely to cause tachycardia in this patient ?

A amphetamine
B dobutamine
C epinephrine
D isoproterenol
E norepinephrine
__________________
Everything is possible for him who believes (MARK 9:23)
245/247/passed on 1st attempt/223/2mos Obsie /3 US LORS/visa not needed/2008 grad
Reply With Quote Quick reply to this message
The above post was thanked by:
alice (10-14-2012), dr.Zh (10-15-2012), MANIAKOS (10-14-2012)



  #2  
Old 10-14-2012
USMLE Forums Master
 
Steps History: 1+CK+CS
Posts: 1,039
Threads: 189
Thanked 561 Times in 319 Posts
Reputation: 571
Default my answer :)

A amphetamine
Reply With Quote Quick reply to this message
  #3  
Old 10-14-2012
USMLE Forums Veteran
 
Steps History: 1+CK+CS+3
Posts: 207
Threads: 19
Thanked 325 Times in 98 Posts
Reputation: 335
Default D

I would go with D, the rest of them have direct influence on heart rate... i think?
Reply With Quote Quick reply to this message
 
  #4  
Old 10-14-2012
Kabutar111's Avatar
USMLE Forums Guru
 
Steps History: Not yet
Posts: 414
Threads: 30
Thanked 87 Times in 70 Posts
Reputation: 97
Send a message via Skype™ to Kabutar111
Default

Will go with here , untill n unless there it's 3 step question
__________________
There is no shortcut to SUCCESS ,and there is no excuse for FALIURE - by Kabutar111
To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.
Reply With Quote Quick reply to this message
  #5  
Old 10-14-2012
beka-CTS's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 763
Threads: 77
Thanked 1,351 Times in 347 Posts
Reputation: 1361
Default

A) amphetamine

new heart has no sympathetic nerves thus they will not be able to act on NE reuptake aka indirect action
__________________
Step 1 - 244 [✔] Step 2 CK - 246 [✔] Step 2 CS [✔] Step 3 - 228 [✔] Match [EMORY SOM] YOG: 2013, 4 Months of USCE University Hospital
Reply With Quote Quick reply to this message
  #6  
Old 10-14-2012
Kabutar111's Avatar
USMLE Forums Guru
 
Steps History: Not yet
Posts: 414
Threads: 30
Thanked 87 Times in 70 Posts
Reputation: 97
Send a message via Skype™ to Kabutar111
Default

Quote:
Originally Posted by beka-CTS View Post
A) amphetamine

new heart has no sympathetic nerves thus they will not be able to act on NE reuptake aka indirect action
Parasympathetic ??
__________________
There is no shortcut to SUCCESS ,and there is no excuse for FALIURE - by Kabutar111
To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.
Reply With Quote Quick reply to this message
  #7  
Old 10-14-2012
beka-CTS's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 763
Threads: 77
Thanked 1,351 Times in 347 Posts
Reputation: 1361
Default

Quote:
Originally Posted by Kabutar111 View Post
Parasympathetic ??
As well as parasympathetic imo.
__________________
Step 1 - 244 [✔] Step 2 CK - 246 [✔] Step 2 CS [✔] Step 3 - 228 [✔] Match [EMORY SOM] YOG: 2013, 4 Months of USCE University Hospital
Reply With Quote Quick reply to this message
  #8  
Old 10-15-2012
koolkiller88's Avatar
USMLE Forums Master
 
Steps History: Step 1 Only
Posts: 864
Threads: 62
Thanked 373 Times in 224 Posts
Reputation: 383
Default

Amphetamine
As I think transplanted heart won't have nerve innervation.
__________________
One day i will infect these microbes and they will search for "Anti-MEbiotic"....
To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.
Reply With Quote Quick reply to this message
  #9  
Old 10-15-2012
MedicalExaminer's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 824
Threads: 66
Thanked 463 Times in 298 Posts
Reputation: 473
Default A amphetamine

indirect acting sympathomimetics (amphetamine) require innervation which in this particular case is absent

others are direct acting (Beta 1 rec)
__________________
Everything is possible for him who believes (MARK 9:23)
245/247/passed on 1st attempt/223/2mos Obsie /3 US LORS/visa not needed/2008 grad
Reply With Quote Quick reply to this message



Reply

Tags
Pharmacology-, Step-1-Questions

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
Transplanted heart with no nerves! Dr.NickRiviera USMLE Step 1 Forum 20 03-28-2012 04:55 PM
Drug effects on the Eyes Hope2Pass USMLE Step 1 Forum 5 03-21-2012 04:58 PM
Drug effects on cholesterol synthesis? medico.in USMLE Step 1 Forum 5 02-26-2011 04:37 AM
cAMP effects on Potassium channels in the heart Rawalian USMLE Step 1 Forum 2 01-07-2011 09:45 AM
Drug Side Effects! Gold-Turk USMLE Step 1 Forum 1 09-11-2009 09:48 AM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)