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Old 10-27-2012
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3 yo boy has intermittent headche and exophthalmos for 6 months, chronically infected ears and nocturia for 3 months. Exam shows fluid draining from both ears. XR films show multiple discrete,lytic bone lesions and bony destrcutions of the mandible. WHich of the following is the most likley diagnosis ?

A. Histiocytosis

B.Nutritional rickets

C. Osteogenesis imperfecta

D.Osteosarcoma

E.Thalassemia
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Old 10-27-2012
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Default Aaa

Hand schuler dx
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Old 10-27-2012
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yes, A ) hand schuller...

thanks @blade for reminding.... thanks for the question
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Old 10-27-2012
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i go with histiocytosis
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Old 10-27-2012
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Default my answer :)

A. Histiocytosis
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Old 10-28-2012
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Correct Answer Option A is correct

Hand-Schuller-Christian disease.Variant of Histiocytosis x
Triad of:
lytic bone lesions(most commonly,skull)
Diabetes insipidus
exopthalmos.

Mostly seen in children <15yo
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Old 10-28-2012
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Quote:
Originally Posted by Josh George View Post
3 yo boy has intermittent headche and exophthalmos for 6 months, chronically infected ears and nocturia for 3 months. Exam shows fluid draining from both ears. XR films show multiple discrete,lytic bone lesions and bony destrcutions of the mandible. WHich of the following is the most likley diagnosis ?

A. Histiocytosis

B.Nutritional rickets

C. Osteogenesis imperfecta

D.Osteosarcoma

E.Thalassemia
I think its
A. Histiocytosis
but not sure which one
May be that one with berbeck bodies but
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Old 10-28-2012
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Default You're right!

Quote:
Originally Posted by koolkiller88 View Post
I think its
A. Histiocytosis
but not sure which one
May be that one with berbeck bodies but
You're right with Birbeck bodies...don't be confused.You can read more here http://en.wikipedia.org/wiki/Birbeck_granules
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