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Old 11-02-2012
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Default Q: Immunology 4

NK cells are designated by CD16 and CD56 and they are also positive for CD2/LFA-2. Which of the following in involved in Antibody dependent cell-mediated cytotoxicity?
A. CD16
B. CD56
C. CD2
D. LFA-2
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usmlemydream (11-03-2012)



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Old 11-02-2012
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CD16??
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Old 11-02-2012
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B. CD56 ????????
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Old 11-02-2012
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i think i've seen this Q in kaplan.
it was both cd16 and cd56 but more of cd56 (can't remember why)
the other options are responsible for adhesion and diapedesis.

the Ans is cd56
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Old 11-02-2012
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Any other opinion frens?
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Old 11-02-2012
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Quote:
Originally Posted by subbi View Post
Any other opinion frens?
i think it is CD 16------->which can be seen not only in NK cells but other phagocytes too.......CD56 is unique marker for NK cells,but it doesnt specify for ADCC.......(remember doin NBME q based on this)
thanks
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Old 11-03-2012
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Yes frens! the answer is CD16, which is also found in other phagocytes (as explained by Venky..........thanx).............CD16 is a Fc receptor that comes into play in ADCC............
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