The effect of H Pylori treatment on GI malignancy - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 11-06-2012
USMLE Forums Addict
 
Steps History: Not yet
Posts: 110
Threads: 14
Thanked 64 Times in 33 Posts
Reputation: 74
Drug The effect of H Pylori treatment on GI malignancy

Chronic infection with H. pylori. H. pylori is classed by WHO as Type I Carcinogen as it can lead to gastric adenocarcinoma, MALToma and B-call lymphoma. How does anti H pylori treatment regimen change to outcome of these malignancies?
A. Only MALToma may resolve
B. Only B-cell lymphoma may resolve
C. Only gastric adenocarcinoma may resolve
D. MALToma and gastric adenoCa may resolve but B-cell lymphoma doesn't
E. MALToma and B-cell lymphoma may resolve but gastric adenoCa doesn't
F. Gastic adenoCa and B-cell lymphoma may resolve but MALToma doesn't
G. None of the malignancies ever resolve
H. All cancers may resolve
Reply With Quote Quick reply to this message
The above post was thanked by:
MedicalExaminer (11-06-2012), trupti (11-06-2012)



  #2  
Old 11-06-2012
venky2600's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 1,186
Threads: 119
Thanked 816 Times in 434 Posts
Reputation: 826
Send a message via Yahoo to venky2600
Post

haha...i have no idea......but just thinking of C ......

i got one doubt....does the question mean outcome abt. the treatment before getting cancers or treatment after getting malignancies....?

thanks
Reply With Quote Quick reply to this message
  #3  
Old 11-06-2012
rupesh's Avatar
USMLE Forums Guru
 
Steps History: 1 + CS
Posts: 386
Threads: 71
Thanked 193 Times in 109 Posts
Reputation: 203
Send a message via AIM to rupesh
Default D

I thought h pylori causes maltoma and gastric adeno ca
Reply With Quote Quick reply to this message
 
  #4  
Old 11-06-2012
venky2600's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 1,186
Threads: 119
Thanked 816 Times in 434 Posts
Reputation: 826
Send a message via Yahoo to venky2600
Post

Quote:
Originally Posted by rupesh View Post
I thought h pylori causes maltoma and gastric adeno ca
no..i think it causes all 3...actually to say...MALToma is a B cell lymphoma of marginal zone
Reply With Quote Quick reply to this message
  #5  
Old 11-06-2012
USMLE Forums Addict
 
Steps History: Not yet
Posts: 110
Threads: 14
Thanked 64 Times in 33 Posts
Reputation: 74
Default

Quote:
Originally Posted by venky2600 View Post
haha...i have no idea......but just thinking of C ......

i got one doubt....does the question mean outcome abt. the treatment before getting cancers or treatment after getting malignancies....?

thanks
It asks about outcome after getting the cancer that's why the words "may resolve" ...................you know the prognosis of severe metastatic disease..............lol.
Reply With Quote Quick reply to this message
  #6  
Old 11-06-2012
venky2600's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 1,186
Threads: 119
Thanked 816 Times in 434 Posts
Reputation: 826
Send a message via Yahoo to venky2600
Post

thanks..so i would change my answer to H.....(as usual guess) lol
Reply With Quote Quick reply to this message
  #7  
Old 11-06-2012
USMLE Forums Scout
 
Steps History: Not yet
Posts: 52
Threads: 1
Thanked 20 Times in 16 Posts
Reputation: 30
Default

ans: g ; none will resolve
Reply With Quote Quick reply to this message
  #8  
Old 11-06-2012
USMLE Forums Scout
 
Steps History: Not yet
Posts: 52
Threads: 1
Thanked 20 Times in 16 Posts
Reputation: 30
Default

Quote:
Originally Posted by crusader View Post
ans: g ; none will resolve
sorry change my ans to E
Reply With Quote Quick reply to this message
  #9  
Old 11-06-2012
MedicalExaminer's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 824
Threads: 66
Thanked 463 Times in 298 Posts
Reputation: 473
Default

Quote:
Originally Posted by subbi View Post
Chronic infection with H. pylori. H. pylori is classed by WHO as Type I Carcinogen as it can lead to gastric adenocarcinoma, MALToma and B-call lymphoma. How does anti H pylori treatment regimen change to outcome of these malignancies?
A. Only MALToma may resolve
B. Only B-cell lymphoma may resolve
C. Only gastric adenocarcinoma may resolve
D. MALToma and gastric adenoCa may resolve but B-cell lymphoma doesn't
E. MALToma and B-cell lymphoma may resolve but gastric adenoCa doesn't
F. Gastic adenoCa and B-cell lymphoma may resolve but MALToma doesn't
G. None of the malignancies ever resolve
H. All cancers may resolve
I guess its E
__________________
Everything is possible for him who believes (MARK 9:23)
245/247/passed on 1st attempt/223/2mos Obsie /3 US LORS/visa not needed/2008 grad
Reply With Quote Quick reply to this message
  #10  
Old 11-06-2012
blade's Avatar
USMLE Forums Guru
 
Steps History: 1+CK+CS+3
Posts: 358
Threads: 22
Thanked 203 Times in 116 Posts
Reputation: 213
Default DD

DD...does h.pylori play a role in B-lymphoma?it believe it's implicated in only 2 malignancies(adenocarcinoma and maltoma according to Goljan)
__________________
with God,nothing is impossible...PREMATCHED!!!
To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.

Reply With Quote Quick reply to this message
  #11  
Old 11-06-2012
USMLE Forums Addict
 
Steps History: Not yet
Posts: 110
Threads: 14
Thanked 64 Times in 33 Posts
Reputation: 74
Default

Quote:
Originally Posted by blade View Post
DD...does h.pylori play a role in B-lymphoma?it believe it's implicated in only 2 malignancies(adenocarcinoma and maltoma according to Goljan)
Refer Kaplan Pg. 270 too.
Reply With Quote Quick reply to this message
  #12  
Old 11-06-2012
USMLE Forums Scout
 
Steps History: Step 1 Only
Posts: 73
Threads: 7
Thanked 25 Times in 13 Posts
Reputation: 35
Default

i guess its A. only MALT ll resolve.
Reply With Quote Quick reply to this message
  #13  
Old 11-06-2012
trupti's Avatar
USMLE Forums Scout
 
Steps History: Not yet
Posts: 75
Threads: 3
Thanked 45 Times in 21 Posts
Reputation: 55
Default

Quote:
Originally Posted by subbi View Post
Chronic infection with H. pylori. H. pylori is classed by WHO as Type I Carcinogen as it can lead to gastric adenocarcinoma, MALToma and B-call lymphoma. How does anti H pylori treatment regimen change to outcome of these malignancies?
A. Only MALToma may resolve
B. Only B-cell lymphoma may resolve
C. Only gastric adenocarcinoma may resolve
D. MALToma and gastric adenoCa may resolve but B-cell lymphoma doesn't
E. MALToma and B-cell lymphoma may resolve but gastric adenoCa doesn't
F. Gastic adenoCa and B-cell lymphoma may resolve but MALToma doesn't
G. None of the malignancies ever resolve
H. All cancers may resolve
A.only MALTOMA may resolve cant wait for the correct answer though
Reply With Quote Quick reply to this message
  #14  
Old 11-06-2012
blade's Avatar
USMLE Forums Guru
 
Steps History: 1+CK+CS+3
Posts: 358
Threads: 22
Thanked 203 Times in 116 Posts
Reputation: 213
Default HH

Quote:
Originally Posted by subbi View Post
Refer Kaplan Pg. 270 too.
thanx,i will go with "H" then?waiting for answer

@subbi
the question is asking about change in Incidence rate not cure for alraedy established malignancies right?
__________________
with God,nothing is impossible...PREMATCHED!!!
To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.

Reply With Quote Quick reply to this message
  #15  
Old 11-06-2012
USMLE Forums Addict
 
Steps History: Not yet
Posts: 110
Threads: 14
Thanked 64 Times in 33 Posts
Reputation: 74
Default

Quote:
Originally Posted by blade View Post
thanx,i will go with "H" then?waiting for answer

@subbi
the question is asking about change in Incidence rate not cure for alraedy established malignancies right?
I've answered this to Venky................we are familiar with the severe metastatic pictures where we don't expect these to resolve, right?..........question asks "which may resolve or not" after development of this cancer...................however, reverting back by drug is limited by the extension of particular cancer.
Reply With Quote Quick reply to this message



  #16  
Old 11-06-2012
blade's Avatar
USMLE Forums Guru
 
Steps History: 1+CK+CS+3
Posts: 358
Threads: 22
Thanked 203 Times in 116 Posts
Reputation: 213
Default EE

Quote:
Originally Posted by subbi View Post
I've answered this to Venky................we are familiar with the severe metastatic pictures where we don't expect these to resolve, right?..........question asks "which may resolve or not" after development of this cancer...................however, reverting back by drug is limited by the extension of particular cancer.
ok,didnt see that.
adenocarcinoma cant be reversed for sure,MALToma will surely be cured but gambling on B-cell lymphoma
__________________
with God,nothing is impossible...PREMATCHED!!!
To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.

Reply With Quote Quick reply to this message
  #17  
Old 11-06-2012
nishaa's Avatar
USMLE Forums Veteran
 
Steps History: 1+CK+CS
Posts: 203
Threads: 32
Thanked 126 Times in 52 Posts
Reputation: 136
Default G.

answer is G. none of the cancers will resolve
Reply With Quote Quick reply to this message
  #18  
Old 11-06-2012
USMLE Forums Addict
 
Steps History: Not yet
Posts: 110
Threads: 14
Thanked 64 Times in 33 Posts
Reputation: 74
Correct Answer EE is correct!!

Thanx everyone.....................though H.pylori is a reservoir in the stomach, Anti H.pylori regimen doesn't resolve gastric adenocarcinoma.
Reply With Quote Quick reply to this message
The above post was thanked by:
prabin (11-26-2012), venky2600 (11-06-2012)
  #19  
Old 11-06-2012
venky2600's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 1,186
Threads: 119
Thanked 816 Times in 434 Posts
Reputation: 826
Send a message via Yahoo to venky2600
Post

Quote:
Originally Posted by subbi View Post
Thanx everyone.....................though H.pylori is a reservoir in the stomach, Anti H.pylori regimen doesn't resolve gastric adenocarcinoma.
thanks buddy for your explanation and question............

i searched for this and found an article where it says hpylori antibiotic regimen also effective for gastric adeno ca. too ,anyways you may be true as i think it's not yet approved........but just adding to your info here
http://www.cancer.gov/cancertopics/f...-pylori-cancer

thanks
Reply With Quote Quick reply to this message
  #20  
Old 11-06-2012
rupesh's Avatar
USMLE Forums Guru
 
Steps History: 1 + CS
Posts: 386
Threads: 71
Thanked 193 Times in 109 Posts
Reputation: 203
Send a message via AIM to rupesh
Default

this is the hell of the question....OMG i pray this type of question will not be asked at my board question
Reply With Quote Quick reply to this message
  #21  
Old 11-07-2012
koolkiller88's Avatar
USMLE Forums Master
 
Steps History: Step 1 Only
Posts: 864
Threads: 62
Thanked 372 Times in 224 Posts
Reputation: 382
Default

Quote:
Originally Posted by subbi View Post
Chronic infection with H. pylori. H. pylori is classed by WHO as Type I Carcinogen as it can lead to gastric adenocarcinoma, MALToma and B-call lymphoma. How does anti H pylori treatment regimen change to outcome of these malignancies?
A. Only MALToma may resolve
B. Only B-cell lymphoma may resolve
C. Only gastric adenocarcinoma may resolve
D. MALToma and gastric adenoCa may resolve but B-cell lymphoma doesn't
E. MALToma and B-cell lymphoma may resolve but gastric adenoCa doesn't
F. Gastic adenoCa and B-cell lymphoma may resolve but MALToma doesn't
G. None of the malignancies ever resolve
H. All cancers may resolve
D. MALToma and gastric adenoCa may resolve but B-cell lymphoma doesn't
????
Just an guess but that raise a concern. How exactly H pylori cause B cell lymphma?? Genetic mutation
I always thought (as goljian mentioned) H pylori causes gastric adenoma or low grade lymphoma (to me it is MALToma)
Not sure
__________________
One day i will infect these microbes and they will search for "Anti-MEbiotic"....
To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.
Reply With Quote Quick reply to this message
  #22  
Old 11-07-2012
koolkiller88's Avatar
USMLE Forums Master
 
Steps History: Step 1 Only
Posts: 864
Threads: 62
Thanked 372 Times in 224 Posts
Reputation: 382
Default

Quote:
Originally Posted by subbi View Post
Thanx everyone.....................though H.pylori is a reservoir in the stomach, Anti H.pylori regimen doesn't resolve gastric adenocarcinoma.
bro what you mean by "H pylori being a reservoir"??? I seems lost in H pylori world
__________________
One day i will infect these microbes and they will search for "Anti-MEbiotic"....
To view links or images in signatures your post count must be 10 or greater. You currently have 0 posts.
Reply With Quote Quick reply to this message
  #23  
Old 11-07-2012
USMLE Forums Addict
 
Steps History: Not yet
Posts: 110
Threads: 14
Thanked 64 Times in 33 Posts
Reputation: 74
Default

Quote:
Originally Posted by koolkiller88 View Post
bro what you mean by "H pylori being a reservoir"??? I seems lost in H pylori world
I mean H.pylori resides in stomach...............
Reply With Quote Quick reply to this message
  #24  
Old 11-07-2012
USMLE Forums Addict
 
Steps History: Not yet
Posts: 110
Threads: 14
Thanked 64 Times in 33 Posts
Reputation: 74
Default

Quote:
Originally Posted by venky2600 View Post
thanks buddy for your explanation and question............

i searched for this and found an article where it says hpylori antibiotic regimen also effective for gastric adeno ca. too ,anyways you may be true as i think it's not yet approved........but just adding to your info here
http://www.cancer.gov/cancertopics/f...-pylori-cancer

thanks
Thanx for the article fren!..................ya i read this but it points out the possible decrease in incidence of gastric adenoca.................not the point about resolving.............nevertheless, i'm thankful to you since the article also informs about possible decrease in esophageal ca by presence of H. pylori............


@Kookkiller.................as venky had explained, MALToma may be subclassified as a part of B-cell lymphoma coz proliferation of B cells occurs.........thanx.
Reply With Quote Quick reply to this message



Reply

Tags
Gastrointestinal-Tract-, Pathology-, Step-1-Questions

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
What side effect of vaginal infection treatment? Casandra USMLE Step 1 Forum 1 07-27-2012 01:27 PM
How to confirm malignancy? anomali USMLE Step 1 Forum 6 06-16-2012 09:00 PM
Diagnosis and Treatment of Prochlorperazine Side Effect! ricko335 USMLE Step 1 Forum 12 04-21-2012 08:00 AM
H. Pylori Treatment Follow Up! ag2011n USMLE Step 2 CK Forum 6 09-14-2011 10:20 PM
Monitoring the treatment for H Pylori! usmlemydream USMLE Step 1 Forum 16 06-23-2011 05:57 PM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)