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Old 11-15-2012
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Arrow Billy Step 1 Questions # 83

An infant girl presents with cyanosis 4 hours after birth. A physician diagnoses her with a condition that develops due to a failure of neural crest cell migration that results in a nonspiraling aorticopulmonary septum. A careful interview of the mother reveals that she has a disease that predisposed her child to this congenital condition. Which of the following collections of symptoms is this infant’s mother most likely experiencing?


(A) Arachnodactyly, hyperextensible joints, and aortic aneurysm
(B) Cold intolerance, delayed refl exes, constipation
(C) Megaloblastic anemia without neurologic symptoms
(D) Mild fever with a descending maculopapular rash and clear buccal mucosa
(E) Polydipsia, polyuria, and blurred vision

Last edited by billy; 11-15-2012 at 03:12 AM.
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Old 11-15-2012
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Default EE

E..transposition of the great vessels common from diabetic mothers
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Old 11-15-2012
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Quote:
Originally Posted by blade View Post
E..transposition of the great vessels common from diabetic mothers
Absolutely agree with BLADE,its e)
thanks for q.
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Old 11-15-2012
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Yes its transposition of great vessels .. Failure of AP septum to spiral.. Common in infants with diabetic mothers..oxygen doesnt improve the cyanosis.. Actually its not good idea to give oxygen since it can cause the situation to be more cyanosis .. Pg should be given to open the ductus..
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Old 11-16-2012
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Correct Answer E is correct

This question requires three steps to answer. First, the clinical scenario should be recognized as transposition of the great vessels. Early cyanosis is typically one of three conditions: Transposition, Tetralogy of Fallot, or Truncus arteriosus (the 3 Ts). Of these, only transposition is due to nonspiral development of the aorticopulmonary septum. Second, it must be known that maternal diabetes increases the risk of having a child with transposition. Finally, the common symptoms of diabetes must be known: polydipsia, polyuria, and blurred vision.
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Default my answer :)

E) Polydipsia, polyuria, and blurred vision
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Old 11-16-2012
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(E) Polydipsia, polyuria, and blurred vision

Remember reading somewhere that DM is risk factor of transposition of great vessels.
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