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Old 08-29-2010
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Pancreas Pancreatic Necrosis

What type of necrosis is pancreatitis (due to the trypsin/phosplipases destroying the pancreas itself)?? it was a question on a NBME, and i was confused between fat, coagulative, caseous,etc?
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Old 08-29-2010
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Fat necrosis???
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Old 08-29-2010
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fat necrosis...for sure..
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Old 08-29-2010
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Originally Posted by Androide89 View Post
What type of necrosis is pancreatitis (due to the trypsin/phosplipases destroying the pancrease itself)?? it was a question on a nbme, and i was confused between fat,coagulative,caseous,etc?
Yes definitely fat necrosis....

But guys what will be the type of necrosis in pancreas in case of pancreatic pseudo-cyst formation ....

Fat necrosis or liquefactive necrosis ??
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Old 08-29-2010
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it will be liquefactive i think..as there is enzymatic destruction....
hmm....our books says liquefactive only occurs in BRAIN....but it occurs in wet gangrene too.....
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Old 08-29-2010
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Well in pancreatitis there is also enzymatic destruction of the pancreas and we call it fat necrosis...

May be it is called liquefactive due to the infection and resulting pus formation.....
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ya thats wut i was confused about i thought the pancreatitis itself is due to liquiefactive necrosis (due to neutrophil/macrophage releasing enzymes) and then the peripheral fat next to the pancreas was fat necrosis (due to the release of lipases from the necrotic pancreas)
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Quote:
Originally Posted by Androide89 View Post
ya thats wut i was confused about i thought the pancreatitis itself is due to liquiefactive necrosis (due to neutrophil/macrophage releasing enzymes) and then the peripheral fat next to the pancreas was fat necrosis (due to the release of lipases from the necrotic pancreas)
yep thats what pathoma says exactly but go with fat necrosis b/c thats what the boards what u to know..im saying after doing all of uworld and nbmes.
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