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  #1  
Old 12-06-2012
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Default Two questions

I'm so frustrated! Different books- different facts!
So first question- is Acetyl-CoA obligate or alosteric activator of pyruvat carboxylase?
Second one- embryology of vagina- first 1/3 derives from paramesonephric duct, and second 2/3 from urogenital sinus. Or is it 2/3, 1/3?
It seems like FA 2012 is so full of mistakes and I'm not quite sure that Errata are ok.
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  #2  
Old 12-06-2012
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Acetyl-CoA is obligate, if you don't have acetyl-Coa you will go to Lactate. (so you have to have it unlike allosteric wich means the enzyme is able to function without activator like fructose 2,6 bisphosphonate.)Pyruvate Carbosylase is activated by acetyl-CoA.

Paramesonephric (mulerian) duct: upper 1/3 of vagina.
Lower 2/3 from urogenital sinus.

I checked them base of FA 2011 (I had checked it with DIT) and with uworld.

Good Luck.
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KovachMarina (12-06-2012), Lara (12-06-2012), MiSeRy (12-06-2012), vnagubandi (12-06-2012)
  #3  
Old 12-06-2012
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¨Tnx! What confused me is that I did UW offline from 2007 and there was a question with Acetyl CoA as an allosteric activator. And, about embriology- seems like something is wrong with Errata for FA 2012.
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Old 12-06-2012
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ya,
you may want to pay and start the new uworld on line. A lot of things keeps changing, like medications, the way of diagnosis, genetic, ratio of MCC of diseases. You don't want to get confused after spending so much time studying.
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  #5  
Old 12-06-2012
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Of course, but I thought to do new UW version after first reading, and that it is ok to do 2007 version after each chapter. Also, I do not think that this with coenzyme is hot topic for scientists.
Tnx again!
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