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Old 12-18-2012
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Default NBME 5 Q - explain please! :(

Which of the following neurotransmitters is released in excess following ischemia and can initiate a receptor-mediated Ca2+ influx that leads to neuronal death?

A. GABA
B. Glutamate
C. Glycine
D. Histamine
E. Norepinephrine
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Old 12-18-2012
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Glutamate

- has excitotoxicity function.
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Old 12-18-2012
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B Glutamate as it excitatory,act by NMDA receptor which causes influx of Ca. glycine is it's co-stimulator. Gaba is inhibitor n act by Cl influx. Histamine and norepinephrine act by G coupled receptor.
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