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Old 12-24-2012
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Bacteria EHEC Inflammatory or Not?

EIEC = Invasive so it produces Inflammatory diarrhea..
EHEC = Non invasive, NO fever, NO PMNs., so it is inflammatory OR non inflammatory??

FA says EHEC's verotoxin produces INFLAMMATION


plz explain
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Old 12-25-2012
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Can anyone explain .....?????????????
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Old 12-25-2012
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EHEC Is "non invasive" but it produces inflammation because the toxin alone (shiga like toxin) causes necrosis and inflammation.
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Old 12-25-2012
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so the diarrhea due to EHEC is an INFLAMMATORY one right?
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Old 12-25-2012
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EHEC is moderately invasive from what I read. It uses bacterial fimbriae for attachment and has a phage encoded shiga-like toxin that target intestinal epithelial cells and cause death causing an inflammatory response. So yes there is inflammation.
..Apparently kaplan says no PMN's but harrison's states there are fecal leukocytes present, but no fever.
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