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Old 02-01-2013
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Blood Heparin and Platelet Factor 4!

Heparin Rx> heparin-factor 4 complex > antibody form )activate platelets > thrombus ) thrombocytopenia . Net result is decrease Factor 4 , and also Decrease platelets .
But factor 4 is also known as CALCIUM , , does it make sense to say that HEPARIN INDUCED THROMBOCYTOPENIA can cause HYPOCALCEMIA ? and if yes , can i start derive some pathophysiology stories from here , like increase PTH , tetany and some other pathophys? help please

Last edited by koyi; 02-01-2013 at 07:45 AM.
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The above post was thanked by:
amresh kumar (02-02-2013)



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Old 02-02-2013
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Default study way

i appreciate ur way of thinking and study
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  #3  
Old 02-02-2013
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You made me answer this......................lol...............In HIT, antibody is directed to "Platelet Factor 4" (which is a platelet released cytokine), not against "Clotting Factor 4" (which is calcium)..........thanx.
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