PAH versus Inulin Renal Excretion! - USMLE Forums
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Old 02-17-2013
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Kidney PAH versus Inulin Renal Excretion!

can someone please explain what the difference between secretion, excretion, filtration and excretion is??

what does it mean that PAH an estimate of renal blood flow because it is filtered and secreted?
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Old 02-17-2013
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Filtration means whether or not the particle filtered/passed through the glomeruli and into the proximal tubules of the nephron. Ex. Glucose, amino acids and various electrolytes pass through. But proteins (ex. albumin) generally don't.

Secretion means, after the blood passes through the glomeruli (where filtration occurs) and reaches the efferent arteriole and (more importantly) peritubular capillaries, is there secretion ( usually active transport) of a that particle from the capillaries to the tubules. This is true with PAH where most of it is secreted from the peritubular capillaires into the tubules rather than filtered at the glomeruli.

Reabsorption is when the particle that was filtered into the renal tubules is reabsorbed back into the peritubular capillaries. True of glucose, aa and most electrolytes.

Excretion is simply what you excrete in the urine. Basically for a particule of interest. Excretion = Filtration + Secretion - Reabsorption

Hope that helps
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Old 02-17-2013
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thank you!!!!!

to simplify do you mean secretion is when the substance is moved from the blood to the kidney? im still not grasping that one
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Old 02-18-2013
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Quote:
to simplify do you mean secretion is when the substance is moved from the blood to the kidney?
Yes, that's right. It's moved from the capillaries to the renal tubules.
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